| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3742516 | Binding | Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay | Rattus norvegicus | 23 | ALA3739289 | cell-based format | Scientific Literature | |
| 2. | ALA3742517 | Binding | Inhibition of UT-B in rat whole blood after 15 mins by RBC lysis assay | Rattus norvegicus | 23 | ALA3739289 | tissue-based format | Scientific Literature | |
| 3. | ALA3742518 | Binding | Reversible inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells at IC50 measured 15 mins post compound washout by fluorescence assay | Rattus norvegicus | 1 | ALA3739289 | cell-based format | Scientific Literature | |
| 4. | ALA3742519 | Binding | Non competitive inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells at IC50 after 15 mins by fluorescence assay in presence of urea | Rattus norvegicus | 1 | ALA3739289 | cell-based format | Scientific Literature | |
| 5. | ALA3742520 | ADME | Metabolic stability in rat liver microsomes assessed as compound remaining after 15 mins by RP-HPLC analysis in presence of NADPH | Rattus norvegicus | 4 | ALA3739289 | tissue-based format | Scientific Literature | |
| 6. | ALA3742760 | ADME | Drug metabolism in rat liver microsomes assessed as cytochrome P450 monooxygenase-mediated oxidation by LC/MS analysis | Rattus norvegicus | 4 | ALA3739289 | tissue-based format | Scientific Literature | |
| 7. | ALA3742761 | ADME | Drug metabolism in rat liver microsomes assessed as [M+ H-16] formation by LC/MS analysis | Rattus norvegicus | 1 | ALA3739289 | tissue-based format | Scientific Literature | |
| 8. | ALA3742762 | Binding | Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 40 secs by fluorescence assay | Rattus norvegicus | 1 | ALA3739289 | cell-based format | Scientific Literature | |
| 9. | ALA5231867 | Binding | Inhibition of UT-B in mouse erythrocyte incubated for 15 mins by erythrocyte osmotic lysis assay | Mus musculus | 4 | ALA5230131 | cell-based format | Scientific Literature | |
| 10. | ALA5231868 | Binding | Inhibition of rat UT-A1 expressed in MDCK cells co-transfected with AQP1 and YFP with assessed as inhibition of urea transport incubated for 15 mins by microplate reader assay | Rattus norvegicus | 5 | ALA5230131 | cell-based format | Scientific Literature |
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