| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3744250 | Binding | Antagonist activity at human EP4 receptor | Homo sapiens | 11 | ALA3739413 | single protein format | Scientific Literature | |
| 2. | ALA3744251 | Functional | Antagonist activity at human EP4 receptor in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation | Homo sapiens | 11 | ALA3739413 | cell-based format | Scientific Literature | |
| 3. | ALA3744252 | Binding | Antagonist activity at EP4 receptor in human whole blood assessed as reversal of inhibition of PGE2 mediated LPS-induced TNF alpha production pretreated for 30 mins using 3,3',5,5' tetramethylbiphenyl-4,4'-diamine substrate measured after 20 to 24 hrs by immunoassay | Homo sapiens | 11 | ALA3739413 | tissue-based format | Scientific Literature | |
| 4. | ALA3744257 | ADME | Drug metabolism in rat hepatic microsomes incubated for 30 mins in presence of NADPH | Rattus norvegicus | 3 | ALA3739413 | assay format | Scientific Literature | |
| 5. | ALA3744258 | ADME | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA3739413 | organism-based format | Scientific Literature | |
| 6. | ALA3744259 | ADME | Cmax in rat at 5 mg/kg, po | Rattus norvegicus | 3 | ALA3739413 | organism-based format | Scientific Literature | |
| 7. | ALA3744260 | ADME | Tmax in rat at 5 mg/kg, po | Rattus norvegicus | 3 | ALA3739413 | organism-based format | Scientific Literature | |
| 8. | ALA3744261 | ADME | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 3 | ALA3739413 | organism-based format | Scientific Literature | |
| 9. | ALA3744262 | Unassigned | Ratio of Cmax in rat to IC50 for EP4 in human whole blood | 3 | ALA3739413 | tissue-based format | Scientific Literature | ||
| 10. | ALA3744263 | Binding | Antagonist activity at human EP1 receptor | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 11. | ALA3744264 | Binding | Antagonist activity at human EP2 receptor | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 12. | ALA3744265 | Binding | Antagonist activity at human EP3 receptor | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 13. | ALA3744266 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 14. | ALA3744267 | ADME | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 15. | ALA3744268 | ADME | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 16. | ALA3744269 | ADME | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 17. | ALA3744270 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 18. | ALA3744271 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 19. | ALA3744272 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA3739413 | single protein format | Scientific Literature | |
| 20. | ALA3744273 | Binding | Selectivity ratio of Ki for human EP2 receptor to Ki for human EP4 receptor | Homo sapiens | 1 | ALA3739413 | assay format | Scientific Literature |
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