# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3743442 | B | Inhibition of IL4-induced STAT6 phosphorylation at tyrosine 641 in human Beas-2B cells at 0.05 to 5 uM incubated for 2 hrs followed by stimulation with IL4 for 1 hr by Western blot assay | Homo sapiens | 1 | ALA3739303 | cell-based format | Scientific Literature | |
2. | ALA3743445 | B | Inhibition of EGF-induced AKT phosphorylation at S473 in human MDA-MB-468 cells at 100 nM incubated for 2 hrs followed by stimulation with EGF for 1 hr by Western blot assay | Homo sapiens | 1 | ALA3739303 | cell-based format | Scientific Literature | |
3. | ALA3743446 | A | Cytotoxicity against human MDA-MB-468 cells assessed as cell proliferation after 72 hrs by MTS assay | Homo sapiens | 6 | ALA3739303 | cell-based format | Scientific Literature | |
4. | ALA3743447 | B | Inhibition of IL6-induced STAT1 phosphorylation at Y701 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 and IL6 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
5. | ALA3743448 | B | Inhibition of IL6-induced STAT3 phosphorylation at Y705 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
6. | ALA3743449 | B | Inhibition of IL2-induced STAT5 phosphorylation at Y694 in CD4+ T lymphocytes isolated from C57BL/6J mouse at 0.5 to 5 uM preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 and IL2 for 15 mins by Western blot analysis | Mus musculus | 5 | ALA3739303 | cell-based format | Scientific Literature | |
7. | ALA3743647 | B | Inhibition of IL4-induced STAT6 phosphorylation at Y641 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 and IL4 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
8. | ALA3743650 | A | Cytotoxicity against human BEAS2B cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 4 | ALA3739303 | cell-based format | Scientific Literature |