| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3742597 | B | Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residual activity at 10 uM measured every 30 to 60 seconds for 60 mins | Homo sapiens | 58 | single protein format | Scientific Literature | ||
| 2. | ALA3742598 | B | Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residual activity measured every 30 to 60 seconds for 60 mins | Homo sapiens | 58 | single protein format | Scientific Literature | ||
| 3. | ALA3742599 | A | Cytotoxicity against human HCT116 cells assessed as cell death at 25 uM after 20 hrs by celltiter blue assay (Rvb = 0.4%) | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 4. | ALA3742602 | B | Inhibition of Rce1 in human HCT116 cells assessed as mislocalization of EGFP-K-Ras in plasma membrane at 25 uM after 24 hrs by fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA3742603 | B | Inhibition of human FACE1-mediated CaaX protease activity at 10 uM measured every 30 to 60 seconds for 60 mins | Homo sapiens | 19 | single protein format | Scientific Literature |
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