# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3744105 | F | Antagonist activity against human GPR40 expressed in HEK293s FLPIN cells assessed as elaidic acid stimulated IP1 release after 2 hrs by TR-FRET analysis | Homo sapiens | 47 | ALA3739339 | cell-based format | Scientific Literature | |
2. | ALA3744106 | P | Lipophilicity, log D of the compound at pH 7.4 | 47 | ALA3739339 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3744107 | P | Solubility of compound | 4 | ALA3739339 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3744108 | A | Intrinsic clearance in rat hepatocytes measured per 10'6 cells | Rattus norvegicus | 3 | ALA3739339 | cell-based format | Scientific Literature | |
5. | ALA3744109 | A | Intrinsic clearance in human liver microsomes measured per 10'6 cells | Homo sapiens | 3 | ALA3739339 | tissue-based format | Scientific Literature | |
6. | ALA3744110 | B | Inhibition of human ERG | Homo sapiens | 3 | ALA3739339 | single protein format | Scientific Literature | |
7. | ALA3744111 | B | Antagonist activity against rat GPR40 | Rattus norvegicus | 3 | ALA3739339 | single protein format | Scientific Literature | |
8. | ALA3744112 | A | Fraction unbound in rat plasma | Rattus norvegicus | 3 | ALA3739339 | cell-free format | Scientific Literature | |
9. | ALA3744113 | A | Fraction unbound in human plasma | Homo sapiens | 3 | ALA3739339 | cell-free format | Scientific Literature | |
10. | ALA3744114 | A | Clearance in rat | Rattus norvegicus | 3 | ALA3739339 | organism-based format | Scientific Literature | |
11. | ALA3744115 | A | Unbound clearance in rat | Rattus norvegicus | 3 | ALA3739339 | organism-based format | Scientific Literature | |
12. | ALA3744116 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 3 | ALA3739339 | organism-based format | Scientific Literature | |
13. | ALA3744117 | A | Oral bioavailability in rat | Rattus norvegicus | 3 | ALA3739339 | organism-based format | Scientific Literature | |
14. | ALA3744118 | A | Oral absorption in rat | Rattus norvegicus | 3 | ALA3739339 | organism-based format | Scientific Literature |