# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3745054 | F | Antimalarial activity against Plasmodium falciparum 3D7 infected in human erythrocytes assessed as growth inhibition after 48 hrs by SYBR Green 1 staining-based fluorescence assay | Plasmodium falciparum | 22 | ALA3739389 | organism-based format | Scientific Literature | |
2. | ALA3745055 | F | Antimalarial activity against drug resistant Plasmodium falciparum W2 infected in human erythrocytes assessed as growth inhibition after 48 hrs by SYBR Green 1 staining-based fluorescence assay | Plasmodium falciparum | 5 | ALA3739389 | organism-based format | Scientific Literature | |
3. | ALA3745056 | F | Antimalarial activity against drug resistant Plasmodium falciparum TM90C2B infected in human erythrocytes assessed as growth inhibition after 48 hrs by SYBR Green 1 staining-based fluorescence assay | Plasmodium falciparum | 5 | ALA3739389 | organism-based format | Scientific Literature | |
4. | ALA3745057 | P | Kinetic solubility of the compound in phosphate buffer at pH 1 at 200 uM | 7 | ALA3739389 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3745058 | P | Kinetic solubility of the compound in fixanal buffer at pH 7.4 at 200 uM | 7 | ALA3739389 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA3745061 | A | Inhibition of cytochrome b-c1 complex bovine heart mitochondrial membranes assessed as reduction in cytochrome c reductase activity using decylubiquinol as substrate at 100 uM by UV-visible spectrophotometric analysis | Bos taurus | 6 | ALA3739389 | assay format | Scientific Literature | |
7. | ALA3745062 | A | Inhibition of cytochrome b-c1 complex bovine heart mitochondrial membranes assessed as reduction in cytochrome c reductase activity using decylubiquinol as substrate at 1 uM by UV-visible spectrophotometric analysis | Bos taurus | 6 | ALA3739389 | assay format | Scientific Literature | |
8. | ALA3745063 | B | Inhibition of yeast DHODH/GFP expressed in plasmodium falciparum 3D7 | Saccharomyces cerevisiae | 2 | ALA3739389 | assay format | Scientific Literature | |
9. | ALA4723090 | B | Allosteric inhibition of MAT2A (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as reduction in S-adenosyl-methionine formation using methionine as substrate in presence of ATP by ELISA | Homo sapiens | 1 | ALA4715850 | assay format | Scientific Literature |