# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3750668 | B | Inhibition of CYP11B2 in human H285R cells assessed as decrease in [125I] angiotensin-2-induced aldosterone secretion after 24 hrs by RIA | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
2. | ALA3750669 | B | Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate after 2 hrs by scintillation proximity assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA3750670 | B | Selectivity ratio of IC50 for human recombinant CYP11B1 to IC50 for human recombinant CYP11B2 | Homo sapiens | 9 | assay format | Scientific Literature | ||
4. | ALA3750671 | B | Inhibition of human CYP19 at 10 uM preincubated for 10 mins with NADPH followed by protein addition measured after 90 mins by fluorometric analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
5. | ALA3750672 | A | Half life in rat liver microsomes after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
6. | ALA3750673 | A | Half life in human liver microsomes after 30 mins by LC/MS/MS analysis | Homo sapiens | 7 | tissue-based format | Scientific Literature | ||
7. | ALA3750679 | B | Inhibition of recombinant rat CYP11B2 using 11-deoxycorticosterone as substrate after 2 hrs by scintillation proximity assay | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
8. | ALA3751183 | B | Inhibition of MAO-A (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature |