# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3749316 | B | Agonist activity at human GPR55 expressed in CHOK1 cells at 10 uM by pathHunter beta-arrestin assay relative to LPI | Homo sapiens | 24 | ALA3745614 | cell-based format | Scientific Literature | |
2. | ALA3749317 | F | Agonist activity at human GPR55 expressed in HEK293 cells assessed as calcium signalling by fura 2-based digital epifluorescence microscopy | Homo sapiens | 23 | ALA3745614 | cell-based format | Scientific Literature | |
3. | ALA3749318 | F | Antagonist activity at human CBR1 assessed as [35S]GTPgammaS binding at 10 uM by luminescence assay relative to control | Homo sapiens | 27 | ALA3745614 | single protein format | Scientific Literature | |
4. | ALA3749319 | F | Agonist activity at CBR1 (unknown origin) assessed as [35S]GTPgammaS binding at 10 uM by luminescence assay relative to control | Homo sapiens | 27 | ALA3745614 | single protein format | Scientific Literature | |
5. | ALA3749320 | F | Antagonist activity at human CBR2 assessed as [35S]GTPgammaS binding at 10 uM by luminescence assay relative to control | Homo sapiens | 27 | ALA3745614 | single protein format | Scientific Literature | |
6. | ALA3749321 | F | Agonist activity at CBR2 (unknown origin) assessed as [35S]GTPgammaS binding at 10 uM by luminescence assay relative to control | Homo sapiens | 27 | ALA3745614 | single protein format | Scientific Literature | |
7. | ALA3749322 | B | Inhibition of human FAAH expressed in African green monkey COS-7 cell membranes using [3H]-AEA as substrate assessed as residual activity at 10 uM preincubated for 10 mins followed by substrate addition measured after 10 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
8. | ALA3749323 | B | Inhibition of human MGL expressed in HEK239 cells using 2AG as substrate assessed as residual activity at 10 uM preincubated for 10 mins followed by substrate addition measured after 10 mins by HPLC analysis | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
9. | ALA3749324 | B | Inhibition of human ABHD12 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 10 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
10. | ALA3749736 | B | Inhibition of human ABHD12 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 1 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
11. | ALA3749737 | B | Inhibition of human ABHD6 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 10 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
12. | ALA3749738 | B | Inhibition of human ABHD6 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 1 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature | |
13. | ALA3749739 | B | Agonist activity at human GPR55 expressed in CHOK1 cells at 10 uM by pathHunter beta-arrestin assay relative to control | Homo sapiens | 27 | ALA3745614 | cell-based format | Scientific Literature |