# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3748982 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated 5-chloroquinolin-8-yl 3-chloropropane-1-sulfonate formation at 2 mM after 12 hrs by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
2. | ALA3748983 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated 5-chloroquinolin-8-yl 4-chlorobutane-1-sulfonate formation at 2 mM after 12 hrs by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
3. | ALA3749032 | ADME | Metabolic stability in human serum assessed as compound decomposed at 5 mM after 24 hrs by HPLC analysis | Homo sapiens | 1 | ALA3745632 | assay format | Scientific Literature | |
4. | ALA3749034 | ADME | Inhibition of aeromonas proteolytica aminopeptidase using L-leucine-p-nitroanilide as substrate by spectrophotometry | Vibrio proteolyticus | 4 | ALA3745632 | assay format | Scientific Literature | |
5. | ALA3749036 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated 2-methylquinolin-8-ol formation at 2 mM after 12 hrs by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
6. | ALA3749037 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated Isothiazolidine 1,1-dioxide formation at 2 mM after 12 hrs by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
7. | ALA3749040 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated 2-methylquinolin-8-ol formation at 50 uM by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
8. | ALA3749041 | ADME | Drug metabolism in HEPES buffer assessed as aeromonas proteolytica aminopeptidase-mediated Isothiazolidine 1,1-dioxide formation at 50 uM by spectrophotometry | Vibrio proteolyticus | 1 | ALA3745632 | assay format | Scientific Literature | |
9. | ALA3749050 | Physicochemical | Dissociation constant, pKa of the compound | 4 | ALA3745632 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA3749051 | ADME | Drug metabolism in human serum assessed as 2-methylquinolin-8-ol formation at 5 mM after 24 hrs by HPLC analysis | Homo sapiens | 1 | ALA3745632 | cell-free format | Scientific Literature | |
11. | ALA3749052 | ADME | Drug metabolism in human serum assessed as 2-methylquinolin-8-yl 3-aminopropane-1-sulfonate formation at 5 mM after 24 hrs by HPLC analysis | Homo sapiens | 1 | ALA3745632 | cell-free format | Scientific Literature | |
12. | ALA3749053 | ADME | Drug metabolism in CD1 mouse S9 fraction assessed as 2-methylquinolin-8-yl 3-aminopropane-1-sulfonate formation at 5 mM after 3 hrs by HPLC analysis | Mus musculus | 1 | ALA3745632 | assay format | Scientific Literature | |
13. | ALA3749057 | Physicochemical | Retention time of compound by HPLC analysis | 4 | ALA3745632 | small-molecule physicochemical format | Scientific Literature |