# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3748118 | B | Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 staining based flow cytometric analysis | Homo sapiens | 16 | ALA3745686 | assay format | Scientific Literature | |
2. | ALA3748119 | B | Agonist activity at human platelet P2X1 receptor assessed as increase in cytosolic calcium level at 1 uM by FLURO-4 staining based flow cytometric analysis relative to beta,gamma-CH2-ATP | Homo sapiens | 18 | ALA3745686 | assay format | Scientific Literature | |
3. | ALA3748121 | F | Anti-aggregatory activity in human platelet rich plasma assessed as inhibition of 3 uM ADP-induced platelet aggregation measured every 11 secs for 6 mins by 96- well microplate method | Homo sapiens | 16 | ALA3745686 | cell-free format | Scientific Literature | |
4. | ALA3748122 | F | Anti-aggregatory activity in human platelet rich plasma assessed as inhibition of 5 uM ADP-induced platelet aggregation preincubated for 15 mins followed by ADP addition measured every 11 secs for 6 mins by 96- well microplate method | Homo sapiens | 16 | ALA3745686 | cell-free format | Scientific Literature | |
5. | ALA3748123 | F | Anti-aggregatory activity in human platelet rich plasma assessed as inhibition of 20 uM ADP-induced platelet aggregation preincubated for 15 mins followed by ADP addition measured every 11 secs for 6 mins by 96- well microplate method | Homo sapiens | 16 | ALA3745686 | cell-free format | Scientific Literature | |
6. | ALA3748124 | F | Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining based flow cytometric analysis | Homo sapiens | 17 | ALA3745686 | assay format | Scientific Literature | |
7. | ALA3748125 | B | Agonist activity at human platelet P2Y12 receptor assessed as decrease in intra-platelet phosphorylated VASP by FLUO-4 staining based flow cytometric analysis | Homo sapiens | 15 | ALA3745686 | assay format | Scientific Literature | |
8. | ALA3748152 | F | Anti-aggregatory activity in human platelet rich plasma assessed as inhibition of ADP-induced platelet shape change | Homo sapiens | 15 | ALA3745686 | cell-free format | Scientific Literature | |
9. | ALA3748154 | F | Agonist activity at human platelet P2Y1 receptor assessed as increase in cytosolic calcium level by FLUO-4 staining based flow cytometric analysis | Homo sapiens | 15 | ALA3745686 | assay format | Scientific Literature |