| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3748597 | B | Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal cortices | Rattus norvegicus | 32 | assay format | Scientific Literature | ||
| 2. | ALA4431204 | B | Displacement of [3H]MLA from human alpha7 nAChR transfected in human SH-SY5Y cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA4431205 | B | Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA4431206 | B | Displacement of [3H]epibatidine from human alpha4beta2 nAChR transfected in HEK293 cell membranes after 120 mins by liquid scintillation counting | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 5. | ALA4431207 | B | Selectivity index, reciprocal of ratio of Ki for alpha7 nAChR transfected in human SH-SY5Y cells to KI for human alpha4beta2 nAChR transfected in HEK293 cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 6. | ALA4431209 | B | Selectivity index, reciprocal of ratio of Ki for human alpha3beta4 nAChR transfected in HEK293 cells to Ki for human alpha4beta2 nAChR transfected in HEK293 cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 7. | ALA4431223 | B | Displacement of [125I]alpha-bungarotoxin from human N-muscle type nAChR alpha1 expressed in human RD cells at 1 uM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4431224 | B | Displacement of [3H]BRL-43694 from human recombinant 5-HT3 receptor expressed in CHO cells at 100 nM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4431225 | B | Agonist activity at human alpha7 nAChR expressed in human SH-SY5Y cells assessed as increase in intracellular calcium levels at 10 uM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4431226 | B | Agonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as increase in intracellular calcium levels at 10 uM | Homo sapiens | 2 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!