# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3751509 | B | Inhibition of DKK1/LRP6 (unknown origin) expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction at 100 uM after 2 hrs by immunofluorescence method | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
2. | ALA3751510 | A | Cytotoxicity against mouse primary cortical neurons assessed as viable cells at 10 uM after 24 hrs by MTT assay | Mus musculus | 19 | cell-based format | Scientific Literature | ||
3. | ALA3751511 | A | Cytotoxicity against mouse primary cortical neurons assessed viable cells at 100 uM after 24 hrs by MTT assay | Mus musculus | 19 | cell-based format | Scientific Literature | ||
4. | ALA3751512 | B | Inhibition of DKK1-LRP6 interactions in mouse cortical neurons assessed as inhibition of prostaglandinJ2-induced tau phosphorylation at Ser396 residue at 10 uM for 1 hr by western bloting | Mus musculus | 9 | protein format | Scientific Literature | ||
5. | ALA3751610 | B | Inhibition of mouse DKK1 assessed as inhibition of DKK1-alkaline phophatase binding to LRP5 transfected in HEK293 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA3768328 | B | Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned media after 2 hrs by fluorescence microscopic analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
7. | ALA3768331 | B | Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned medium | Homo sapiens | 1 | cell-based format | Scientific Literature |