| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3748820 | B | Inhibition of wild type EML4-ALK (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 2. | ALA3748821 | B | Inhibition of EML4-ALK C1156Y mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 3. | ALA3748822 | B | Inhibition of EML4-ALK F1174L mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 4. | ALA3748823 | B | Inhibition of EML4-ALK L1196M mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 5. | ALA3748824 | B | Inhibition of EML4-ALK L1152R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 6. | ALA3748825 | B | Inhibition of EML4-ALK 1151Tins mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 7. | ALA3748826 | B | Inhibition of EML4-ALK G1202R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 8. | ALA3748827 | B | Inhibition of EML4-ALK G1269A mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 9. | ALA3748828 | B | Inhibition of EML4-ALK S1206Y mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assay | Homo sapiens | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 10. | ALA3748829 | A | Cytotoxicity against mouse BA/F3 cells assessed as cell viability after 72 hrs by MTS assay | Mus musculus | 18 | ALA3745656 | cell-based format | Scientific Literature | |
| 11. | ALA3748830 | B | Inhibition of wild type EML4-ALK (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability at 1 uM after 72 hrs by MTS assay | Homo sapiens | 31 | ALA3745656 | cell-based format | Scientific Literature | |
| 12. | ALA3748831 | B | Inhibition of EML4-ALK G1202R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability at 1 uM after 72 hrs by MTS assay | Homo sapiens | 31 | ALA3745656 | cell-based format | Scientific Literature | |
| 13. | ALA3748832 | A | Cytotoxicity against mouse BA/F3 cells assessed as cell viability at 1 uM after 72 hrs by MTS assay | Mus musculus | 31 | ALA3745656 | cell-based format | Scientific Literature | |
| 14. | ALA3748834 | F | Antiproliferative activity against human NCI-H3122 cells after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 15. | ALA3748835 | F | Antiproliferative activity against human DFCI76 cells expressing EML4-ALK L1152R mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 16. | ALA3748836 | F | Antiproliferative activity against human DFCI114 cells expressing EML4-ALK G1269A mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 17. | ALA3748837 | F | Antiproliferative activity against human Kelly cells expressing EML4-ALK F1174L mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 18. | ALA3748838 | F | Antiproliferative activity against human LAN1 cells expressing EML4-ALK F1174L mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 19. | ALA3748839 | F | Antiproliferative activity against human SH-SY5Y cells expressing EML4-ALK F1174L mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature | |
| 20. | ALA3748840 | F | Antiproliferative activity against human SK-N-SH cells expressing EML4-ALK F1174L mutant after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay | Homo sapiens | 7 | ALA3745656 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!