# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3748912 | Functional | Antiproliferative activity against mouse L1210 cells after 48 hrs by MTT assay | Mus musculus | 11 | ALA3745659 | cell-based format | Scientific Literature | |
2. | ALA3748913 | Functional | Antiproliferative activity against human CEM cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA3745659 | cell-based format | Scientific Literature | |
3. | ALA3748914 | Functional | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA3745659 | cell-based format | Scientific Literature | |
4. | ALA3748915 | Functional | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA3745659 | cell-based format | Scientific Literature | |
5. | ALA3748916 | Functional | Antiproliferative activity against human K562 cells after 72 hrs by MTT assay | Homo sapiens | 9 | ALA3745659 | cell-based format | Scientific Literature | |
6. | ALA3748917 | Functional | Antiproliferative activity against human K562/4 cells after 72 hrs by MTT assay | Homo sapiens | 9 | ALA3745659 | cell-based format | Scientific Literature | |
7. | ALA3749280 | Binding | Inhibition of Top1 (unknown origin)-mediated relaxation of pBR322 DNA at 2.5 uM incubated for 30 mins by ethidium bromide staining-based gel electrophoresis assay | Homo sapiens | 5 | ALA3745659 | single protein format | Scientific Literature | |
8. | ALA3749282 | Binding | Inhibition of Top1 (unknown origin)-mediated relaxation of pBR322 DNA at 0.5 uM incubated for 30 mins by ethidium bromide staining-based gel electrophoresis assay | Homo sapiens | 3 | ALA3745659 | single protein format | Scientific Literature | |
9. | ALA3749283 | Binding | Inhibition of Top2 (unknown origin)-mediated relaxation of pBR322 DNA at 0.5 to 10 uM incubated for 30 mins by ethidium bromide staining-based gel electrophoresis assay | Homo sapiens | 2 | ALA3745659 | single protein format | Scientific Literature | |
10. | ALA3749284 | Functional | Induction of apoptosis in human AGS cells after 24 hrs by annexin V-FITC staining-based flow cytometric analysis | Homo sapiens | 7 | ALA3745659 | cell-based format | Scientific Literature | |
11. | ALA3749326 | Functional | Induction of apoptosis in human AGS cells assessed as necrotic cells at 5 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=1.1%) | Homo sapiens | 1 | ALA3745659 | cell-based format | Scientific Literature | |
12. | ALA3749327 | Functional | Induction of apoptosis in human AGS cells assessed as necrotic cells at 10 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=1.1%) | Homo sapiens | 3 | ALA3745659 | cell-based format | Scientific Literature | |
13. | ALA3749331 | Functional | Induction of apoptosis in human AGS cells assessed as late apoptotic cells at 5 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=5.5%) | Homo sapiens | 1 | ALA3745659 | cell-based format | Scientific Literature | |
14. | ALA3749332 | Functional | Induction of apoptosis in human AGS cells assessed as late apoptotic cells at 10 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=5.5%) | Homo sapiens | 3 | ALA3745659 | cell-based format | Scientific Literature | |
15. | ALA3749336 | Functional | Induction of apoptosis in human AGS cells assessed as early apoptotic cells at 5 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=9.8%) | Homo sapiens | 1 | ALA3745659 | cell-based format | Scientific Literature | |
16. | ALA3749337 | Functional | Induction of apoptosis in human AGS cells assessed as early apoptotic cells at 10 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=9.8%) | Homo sapiens | 3 | ALA3745659 | cell-based format | Scientific Literature | |
17. | ALA3749663 | Functional | Induction of apoptosis in human AGS cells assessed as viable cells at 5 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=83.7%) | Homo sapiens | 1 | ALA3745659 | cell-based format | Scientific Literature | |
18. | ALA3749664 | Functional | Induction of apoptosis in human AGS cells assessed as viable cells at 10 uM after 24 hrs by annexin V-FITC staining-based flow cytometric analysis (Rvb=83.7%) | Homo sapiens | 3 | ALA3745659 | cell-based format | Scientific Literature | |
19. | ALA3749665 | Functional | Upregulation of phosphorylated p53 level in human AGS cells at 1 and 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 7 | ALA3745659 | cell-based format | Scientific Literature | |
20. | ALA3749666 | ADME | Upregulation of total p53 level in human AGS cells at 1 and 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 6 | ALA3745659 | cell-based format | Scientific Literature |