| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3748723 | B | Displacement of [3H]1alpha,25-(OH)2D3 from full-length recombinant rat VDR by scintillation counter | Rattus norvegicus | 6 | ALA3745627 | single protein format | Scientific Literature | |
| 2. | ALA3748724 | B | Potency index, ratio Ki for 1alpha,25(OH)2D3 to Ki for compound for binding affinity to full-length recombinant rat VDR | Rattus norvegicus | 5 | ALA3745627 | single protein format | Scientific Literature | |
| 3. | ALA3748725 | F | Induction of human HL60 cell differentiation assessed as differentiation from promyelocytes to monocytes by NBT assay | Homo sapiens | 6 | ALA3745627 | cell-based format | Scientific Literature | |
| 4. | ALA3748726 | F | Potency index, ratio ED50 of 1alpha,25-(OH)2D3 to ED50 of compound for induction of human HL60 cell differentiation | Homo sapiens | 5 | ALA3745627 | cell-based format | Scientific Literature | |
| 5. | ALA3748727 | B | Transactivation of VDR in rat osteosarcoma cells assessed as 24-hydroxylase transcriptional activity by luciferase reporter gene assay | Rattus norvegicus | 6 | ALA3745627 | cell-based format | Scientific Literature | |
| 6. | ALA3748728 | B | Potency index, ratio ED50 of 1alpha,25-(OH)2D3 to ED50 of compound for transactivation of VDR in rat osteosarcoma cells assessed as 24-hydroxylase transcriptional activity | Rattus norvegicus | 5 | ALA3745627 | cell-based format | Scientific Literature | |
| 7. | ALA3748731 | F | Induction of bone mobilization activity in weaning Sprague-Dawley rat assessed as increase in serum calcium level at 780 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 4.4 to 4.5 mg/dl) | Rattus norvegicus | 5 | ALA3745627 | organism-based format | Scientific Literature | |
| 8. | ALA3748732 | F | Induction of bone mobilization activity in weaning Sprague-Dawley rat assessed as increase in serum calcium level at 260 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 4.4 to 4.5 mg/dl) | Rattus norvegicus | 4 | ALA3745627 | organism-based format | Scientific Literature | |
| 9. | ALA3748733 | F | Induction of bone mobilization activity in weaning Sprague-Dawley rat assessed as increase in serum calcium level at 32 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 4.4 to 4.5 mg/dl) | Rattus norvegicus | 2 | ALA3745627 | organism-based format | Scientific Literature | |
| 10. | ALA3749061 | F | Induction of intestinal calcium transport in weaning Sprague-Dawley rat assessed as ratio of calcium level in serosal to mucosal at 780 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 3.7 to 4.8 No_unit) | Rattus norvegicus | 5 | ALA3745627 | organism-based format | Scientific Literature | |
| 11. | ALA3749062 | F | Induction of intestinal calcium transport in weaning Sprague-Dawley rat assessed as ratio of calcium level in serosal to mucosal at 260 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 3.7 to 4.8 No_unit) | Rattus norvegicus | 4 | ALA3745627 | organism-based format | Scientific Literature | |
| 12. | ALA3749063 | F | Induction of intestinal calcium transport in weaning Sprague-Dawley rat assessed as ratio of calcium level in serosal to mucosal at 32 pmol, ip for 4 consecutive dose at an interval of 24 hrs measured 24 hrs after last dose (Rvb = 3.7 to 4.8 No_unit) | Rattus norvegicus | 2 | ALA3745627 | organism-based format | Scientific Literature |
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