| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3748812 | A | Fraction unbound in C57BL/6j mouse plasma at 10 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 2. | ALA3748813 | T | Toxicity in C57BL/6j mouse assessed as spontaneous locomotory activity upto 10 mg/kg, sc for 90 mins | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 3. | ALA3748814 | F | Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay | Homo sapiens | 20 | ALA3745675 | cell-based format | Scientific Literature | |
| 4. | ALA3748815 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 20 | ALA3745675 | tissue-based format | Scientific Literature | |
| 5. | ALA3749134 | A | Efflux ratio of permeability from basolateral to apical over apical to basolateral side in MDCK cells expressing MDR1 | Canis lupus familiaris | 20 | ALA3745675 | cell-based format | Scientific Literature | |
| 6. | ALA3749135 | A | Permeability in RRCK cells | Canis lupus familiaris | 3 | ALA3745675 | cell-based format | Scientific Literature | |
| 7. | ALA3749136 | A | Ratio of unbound AUC in brain to plasma in C57BL/6j mouse | Mus musculus | 2 | ALA3745675 | organism-based format | Scientific Literature | |
| 8. | ALA3749137 | A | Ratio of unbound AUC in brain to plasma in Wistar Hann rat | Rattus norvegicus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 9. | ALA3749138 | A | Half life in Wistar Hann rat | Rattus norvegicus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 10. | ALA3749139 | A | Clearance in Wistar Hann rat at 0.5 mg/kg, iv administered as bolus dose | Rattus norvegicus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 11. | ALA3749140 | A | Oral bioavailability in Wistar Hann rat | Rattus norvegicus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 12. | ALA3749141 | A | Fraction unbound in C57BL/6j mouse plasma | Mus musculus | 2 | ALA3745675 | cell-free format | Scientific Literature | |
| 13. | ALA3749142 | A | Fraction unbound in Wistar Hann rat brain | Rattus norvegicus | 2 | ALA3745675 | tissue-based format | Scientific Literature | |
| 14. | ALA3749143 | A | Fraction unbound in Wistar Hann rat plasma | Rattus norvegicus | 1 | ALA3745675 | cell-free format | Scientific Literature | |
| 15. | ALA3749144 | A | Fraction unbound in C57BL/6j mouse plasma at 3.2 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 16. | ALA3749145 | A | Fraction unbound in C57BL/6j mouse brain at 3.2 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 17. | ALA3749146 | A | Ratio drug level in brain to plasma in C57BL/6j mouse at 3.2 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 18. | ALA3749147 | A | Ratio of unbound AUC in brain to plasma in C57BL/6j mouse at 3.2 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 19. | ALA3749148 | A | Fraction unbound in C57BL/6j mouse brain at 10 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature | |
| 20. | ALA3749149 | A | Ratio drug level in brain to plasma in C57BL/6j mouse at 10 mg/kg, sc after 1 hr | Mus musculus | 1 | ALA3745675 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!