# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3755988 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak rise rate of left ventricular pressure at 10 umol/L (Rvb = 1117.66 +/- 665.76 to 1242.03 +/- 495.72 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
2. | ALA3755989 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak rise rate of left ventricular pressure at 1 umol/L (Rvb = 1117.66 +/- 665.76 to 1242.03 +/- 495.72 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
3. | ALA3755990 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular diastolic pressure at 100 umol/L (Rvb = -0.04 +/- 0.33 to -0.67 +/- 0.69 mmHg) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
4. | ALA3755991 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular diastolic pressure at 10 umol/L (Rvb = -0.04 +/- 0.33 to -0.67 +/- 0.69 mmHg) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
5. | ALA3755992 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular diastolic pressure at 1 umol/L (Rvb = -0.04 +/- 0.33 to -0.67 +/- 0.69 mmHg) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
6. | ALA3755993 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular systolic pressure at 10 umol/L (Rvb = 20.7 +/- 7.61 to 25.86 +/- 9.41 mmHg) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
7. | ALA3755994 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular systolic pressure at 100 umol/L (Rvb = 20.7 +/- 7.61 to 25.86 +/- 9.41 mmHg) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
8. | ALA3755995 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as left ventricular systolic pressure at 1 umol/L (Rvb = 20.7 +/- 7.61 to 25.86 +/- 9.41 mmHg) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
9. | ALA3757092 | Physicochemical | Retention time of the compound by HPLC- MS/MS analysis | 4 | ALA3751747 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA3757093 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak rise of left ventricular pressure at 100 umol/L (Rvb = 1117.66 +/- 665.76 to 1242.03 +/- 495.72 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
11. | ALA3757094 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak decrease rate of left ventricular pressure at 1 umol/L (Rvb = - 756.58 +/- 265.23 to - 831 +/- 313.09 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
12. | ALA3757095 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak decrease rate of left ventricular pressure at 10 umol/L (Rvb = - 756.58 +/- 265.23 to - 831 +/- 313.09 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
13. | ALA3757096 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as peak decrease rate of left ventricular pressure at 100 umol/L (Rvb = - 756.58 +/- 265.23 to - 831 +/- 313.09 mmHg/s) | Rattus norvegicus | 4 | ALA3751747 | tissue-based format | Scientific Literature | |
14. | ALA3757097 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as heart rate at 1 umol/L (Rvb = 218.67 +/- 20.62 to 260 +/- 21.81 bpm) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
15. | ALA3757098 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as heart rate at 10 umol/L (Rvb = 218.67 +/- 20.62 to 260 +/- 21.81 bpm) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
16. | ALA3757099 | Functional | Positive inotropic activity in Sprague-Dawley rat heart assessed as heart rate at 100 umol/L (Rvb = 218.67 +/- 20.62 to 260 +/- 21.81 bpm) | Rattus norvegicus | 5 | ALA3751747 | tissue-based format | Scientific Literature | |
17. | ALA3757104 | Toxicity | Toxicity in Sprague-Dawley rat heart assessed as arrhythmias | Rattus norvegicus | 5 | ALA3751747 | assay format | Scientific Literature |