# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3755108 | ADME | Stability of the compound in NH4HCO3 buffer assessed as trypsin (unknown origin)-mediated degradation by measuring intact compound level at pH 7.8 at 37 degC after 8 hrs by UPLC analysis | Homo sapiens | 1 | ALA3751758 | assay format | Scientific Literature | |
2. | ALA3755109 | Physicochemical | Stability of the compound in boiling water assessed as compound remaining after 1 hr by UPLC analysis | 1 | ALA3751758 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3755111 | ADME | Stability of the compound in 100 mM sodium citrate buffer assessed as pepsin (unknown origin)-mediated compound degradation by measuring intact compound level at pH 2.5 at 37 degC after 4 hrs by UPLC analysis | Homo sapiens | 3 | ALA3751758 | assay format | Scientific Literature | |
4. | ALA3755113 | ADME | Cytotoxicity against African green monkey Vero cells at 10 uM after 24 hrs by Presto Blue-based cell viability assay | Chlorocebus sabaeus | 1 | ALA3751758 | cell-based format | Scientific Literature | |
5. | ALA3755114 | ADME | Cytotoxicity against HUVEC at 10 uM after 24 hrs by Presto Blue-based cell viability assay | Homo sapiens | 1 | ALA3751758 | cell-based format | Scientific Literature | |
6. | ALA3755115 | ADME | Hemolytic activity in human type O+ erythrocytes up to 10 uM after 4 hrs by spectrophotometric analysis | Homo sapiens | 1 | ALA3751758 | cell-based format | Scientific Literature | |
7. | ALA3755116 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 12600 up to 100 uM by radial diffusion assay | Staphylococcus aureus | 1 | ALA3751758 | organism-based format | Scientific Literature | |
8. | ALA3755117 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 up to 100 uM by radial diffusion assay | Escherichia coli | 1 | ALA3751758 | organism-based format | Scientific Literature | |
9. | ALA3755118 | Functional | Antifungal activity against Candida albicans 11006 up to 100 uM by radial diffusion assay | Candida albicans | 1 | ALA3751758 | organism-based format | Scientific Literature | |
10. | ALA3755119 | Binding | Inhibition of bovine carboxypeptidase A using N-(4-methoxyphenylazoformyl)phenylalanine as substrate at 0.1 to 100 uM | Bos taurus | 1 | ALA3751758 | single protein format | Scientific Literature | |
11. | ALA3755120 | ADME | Stability of the compound in Tris buffer assessed as carboxypeptidase A (unknown origin)-mediated compound degradation by measuring intact compound level at pH 7.5 at 37 degC after 6 hrs by UPLC analysis | Homo sapiens | 1 | ALA3751758 | single protein format | Scientific Literature |