| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3755535 | B | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 1 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA3755536 | B | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 3 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA3755537 | B | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 4 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA3755538 | B | Displacement of 125I-labeled [Nle4,DPhe7]-alpha-MSH from human melanocortin 5 receptor expressed in HEK293 cells incubated for 40 mins by gamma counting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA3755539 | F | Agonist activity at human melanocortin 1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA3755540 | F | Agonist activity at human melanocortin 3 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA3755541 | F | Agonist activity at human melanocortin 4 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA3755542 | F | Agonist activity at human melanocortin 5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation incubated for 3 mins in presence of IBMX | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3755544 | F | Agonist activity at human melanocortin 1 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3755545 | F | Agonist activity at human melanocortin 3 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3755547 | F | Agonist activity at human melanocortin 5 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation incubated for 3 mins relative to MT-2 | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3755736 | B | Selectivity ratio of EC50 for human melanocortin 5 receptor expressed in HEK293 cells to EC50 for human melanocortin 3 receptor expressed in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5164340 | F | Antagonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 10 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA5164342 | F | Agonist activity at human MC1R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5164343 | F | Agonist activity at human MC3R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5164344 | F | Agonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5164345 | F | Agonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as increase in cAMP level by split luciferase cAMP sensor dynamic assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA5164346 | F | Antagonist activity at human MC4R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 70 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA5164347 | F | Antagonist activity at human MC5R transfected in HEK293 cells co-transfected with GScAMP22F assessed as decrease in alpha-MSH induced cAMP level in presence of 500 nM alpha-MSH by split luciferase cAMP sensor dynamic assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5164348 | F | Agonist activity at human MC3R expressed in BHK cells assessed as increase in cAMP level measured upto 0.00005 M incubated for 30 mins by antibody based cAMP detection/FRET analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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