| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3756313 | B | Displacement of [3H]citalopram from SERT in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry | Rattus norvegicus | 15 | tissue-based format | Scientific Literature | ||
| 2. | ALA3756314 | B | Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry | Rattus norvegicus | 16 | tissue-based format | Scientific Literature | ||
| 3. | ALA3756315 | B | Displacement of [3H]ketanserin from 5HT2A in Wistar rat frontal cortex membranes after 1 hr by liquid scintillation spectrometry | Rattus norvegicus | 7 | cell membrane format | Scientific Literature | ||
| 4. | ALA3756320 | F | Antagonist activity at human 5-HT2A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced Ca2+ release at 10 uM by fluorometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3756321 | F | Antagonist activity at human 5-HT2C receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced Ca2+ release at 10 uM by fluorometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3756322 | B | Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor at 1 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA3756323 | B | Displacement of [3H]-LSD from human 5HT2B receptor at 1 uM | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA3756325 | A | Intrinsic clearance in human liver microsomes at 2.5 uM | Homo sapiens | 6 | tissue-based format | Scientific Literature | ||
| 9. | ALA3756326 | A | Intrinsic clearance in mouse liver microsomes at 2.5 uM | Mus musculus | 6 | tissue-based format | Scientific Literature | ||
| 10. | ALA3756327 | A | Apparent permeability of the compound from apical to basolateral side in human vinblastine-treated Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3756529 | A | Efflux ratio of the compound from apical to basolateral side to basolateral to apical side in human vinblastine-treated Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3756530 | A | Potentiation of mCPP-induced hypomotility in NMRI mouse at 20 to 40 mg/kg, ip up to 60 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3756532 | F | Inhibition of mCPP-induced hypomotility in NMRI mouse assessed as reductiion in vertical hypoactivity at 20 to 40 mg/kg, ip up to 60 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3756533 | A | Induction of motor depression in C57BL/6J mouse assessed as total duration of immobility was measured over a period of 6 mins at 20 to 80 mg/kg, ip by tail suspension test | Mus musculus | 1 | organism-based format | Scientific Literature |
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