| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3756853 | B | Inhibition of human 5alpha-1 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione at 10 uM incubated for 30 mins by radioactivity-based HPLC analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA3756854 | B | Inhibition of human 5alpha-1 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione at 2 uM incubated for 30 mins by radioactivity-based HPLC analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA3756855 | B | Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione at 10 uM incubated for 30 mins by radioactivity-based HPLC analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA3756856 | B | Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione at 2 uM incubated for 30 mins by radioactivity-based HPLC analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA3756857 | B | Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by radioactivity-based HPLC analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA3756858 | F | Cytotoxicity against human DU145 cells by rapid colorimetric assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA3756859 | A | Increase in body weight gain in male wistar rat at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=9.412+/-1.632g%) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 8. | ALA3756860 | A | Effect on organ weight in male wistar rat assessed as liver tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=2.994+/- 0.254 g/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 9. | ALA3756861 | F | Effect on organ weight in male wistar rat assessed as ventral prostate tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=59.494+/- 4.733 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 10. | ALA3756862 | F | Effect on organ weight in male wistar rat assessed as dorsal prostate tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=50.325+/-7.519 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 11. | ALA3756863 | A | Effect on organ weight in male wistar rat assessed as seminal vesicles tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=175.439+/-12.833 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 12. | ALA3756864 | A | Effect on organ weight in male wistar rat assessed testis tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=1054.099+/- 55.648 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 13. | ALA3756865 | A | Effect on organ weight in male wistar rat assessed as adrenal tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=14.762 +/-0.600 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 14. | ALA3756866 | F | Effect on organ weight in male wistar rat assessed as vas deferens tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=67.613+/-3.248 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 15. | ALA3756867 | F | Effect on organ weight in male wistar rat assessed as epididymis tissue weight per 100g at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose (Rvb=187.356+/- 5.961 mg/100g) | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 16. | ALA3756868 | F | Decrease in ventral prostate organ weight in male wistar rat at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 17. | ALA3756869 | F | Decrease in dorsal prostate organ weight in male wistar rat at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 18. | ALA3756870 | F | Decrease in vas deferens organ weight in male wistar rat at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 19. | ALA3756871 | F | Decrease in epididymis organ weight in male wistar rat at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 20. | ALA3756873 | T | Toxicity in male wistar rat assessed induction of mortality at 5ml/kg, po qd measured on 15th day after 24 hrs of last dose | Rattus norvegicus | 6 | organism-based format | Scientific Literature |
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