# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3758003 | Binding | Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Mycobacterium tuberculosis | 40 | ALA3751721 | assay format | Scientific Literature | |
2. | ALA3758004 | Binding | Inhibition of Mycobacterium smegmatis GyrB by ATPase assay | Mycolicibacterium smegmatis | 36 | ALA3751721 | single protein format | Scientific Literature | |
3. | ALA3758005 | Binding | Inhibition of Staphylococcus aureus DNA gyrase assessed as inhibition of DNA supercoiling | Staphylococcus aureus | 36 | ALA3751721 | protein complex format | Scientific Literature | |
4. | ALA3758006 | Binding | Inhibition of Escherichia coli DNA gyrase assessed as inhibition of DNA supercoiling | Escherichia coli | 36 | ALA3751721 | assay format | Scientific Literature | |
5. | ALA3758007 | Binding | Inhibition of Pseudomonas aeruginosa DNA gyrase assessed as inhibition of DNA supercoiling | Pseudomonas aeruginosa | 36 | ALA3751721 | protein complex format | Scientific Literature | |
6. | ALA3758008 | Binding | Inhibition of Mycobacterium tuberculosis DNA topoisomerase 1 assessed as DNA relaxation at 50 uM | Mycobacterium tuberculosis | 36 | ALA3751721 | assay format | Scientific Literature | |
7. | ALA3758010 | Functional | Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 28 days by alamar blue assay | Mycobacterium tuberculosis | 40 | ALA3751721 | organism-based format | Scientific Literature | |
8. | ALA3758011 | ADME | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell growth at 50 uM after 72 hrs by MTT assay | Mus musculus | 40 | ALA3751721 | cell-based format | Scientific Literature |