# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3756683 | B | Inhibition of Plasmodium falciparum NMT by 7-diethylamine-3-(4'maleimidylphenyl)-4-methylcoumarin based fluorescence assay | Plasmodium falciparum | 25 | assay format | Scientific Literature | ||
2. | ALA3756684 | B | Inhibition of human NMT1 by 7-diethylamine-3-(4'maleimidylphenyl)-4-methylcoumarin based fluorescence assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
3. | ALA3756685 | B | Selectivity index, ratio of Ki(app) for human NMT1 to Ki(app) for Plasmodium falciparum NMT | 20 | assay format | Scientific Literature | |||
4. | ALA3773952 | B | Binding affinity to Leishmania donovani N-myristoyltransferase by fluorescence analysis | Leishmania donovani | 15 | assay format | Scientific Literature | ||
5. | ALA3773953 | B | Binding affinity to human N-myristoyltransferase by fluorescence analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
6. | ALA3773954 | F | Antileishmanial activity against Leishmania donovani MHOM/ET/67/HU3 amastigotes infected in BaLB/c mouse BMDM cells after 72 hrs by Alamar Blue assay | Leishmania donovani | 5 | organism-based format | Scientific Literature | ||
7. | ALA3773955 | A | Cytotoxicity in BALB/c mouse BMDM cells after 72 hrs by Alamar Blue assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
8. | ALA3773957 | A | Therapeutic index, ratio of LD50 for BALB/c mouse BMDM cells to EC50 for Leishmania donovani amastigotes | 3 | cell-based format | Scientific Literature |