| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3760529 | F | Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay | Homo sapiens | 17 | ALA3758116 | cell-based format | Scientific Literature | |
| 2. | ALA3760530 | F | Agonist activity at recombinant human NMU1 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay relative to human NmU | Homo sapiens | 11 | ALA3758116 | cell-based format | Scientific Literature | |
| 3. | ALA3760532 | F | Agonist activity at recombinant human NMU2 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay | Homo sapiens | 17 | ALA3758116 | cell-based format | Scientific Literature | |
| 4. | ALA3760533 | F | Agonist activity at recombinant human NMU2 expressed in HEK293 cells assessed as change in intracellular calcium flux by fluorescence assay relative to human NmU | Homo sapiens | 11 | ALA3758116 | cell-based format | Scientific Literature | |
| 5. | ALA3760536 | F | Anorectic activity in DIO C57BL/6 mouse assessed as decrease in body weight at 2.2 mg/kg, sc administered every 2 days for 21 days | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 6. | ALA3760537 | F | Anorectic activity in DIO C57BL/6 mouse assessed as decrease in body weight at 2.2 mg/kg, sc administered every 4 days for 21 days | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 7. | ALA3760538 | F | Anorectic activity in DIO C57BL/6 mouse assessed as decrease in body weight at 2.2 mg/kg, sc administered every 7 days for 21 days | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 8. | ALA3760539 | T | Toxicity in DIO C57BL/6 mouse assessed as gastric emptying at 2.2 mg/kg, sc measured within 24 hrs | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 9. | ALA3760540 | F | Anorectic activity in DIO C57BL/6 mouse assessed as decrease in body weight at 2.2 mg/kg, sc administered once a week for 21 days | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 10. | ALA3760541 | A | Half life in C57BL/6 mouse at 10 mg/kg by LC/MS analysis | Mus musculus | 2 | ALA3758116 | organism-based format | Scientific Literature | |
| 11. | ALA3760542 | A | Tmax in C57BL/6 mouse at 10 mg/kg by LC/MS analysis | Mus musculus | 2 | ALA3758116 | organism-based format | Scientific Literature | |
| 12. | ALA3760544 | A | Metabolic stability in mouse plasma assessed as compound remaining at 25 uM measured at 24 hrs by LC/MS analysis | Mus musculus | 1 | ALA3758116 | cell-free format | Scientific Literature | |
| 13. | ALA3760546 | A | Metabolic stability in mouse plasma assessed as compound remaining at 25 uM measured after 6 days by LC/MS analysis | Mus musculus | 2 | ALA3758116 | cell-free format | Scientific Literature | |
| 14. | ALA3760749 | F | Antiobesity activity in DIO C57BL/6 mouse assessed as decrease in abdominal fat content at 2.2 mg/kg, sc administered every 2 days for 21 days (Rvb = 8.1 +/- 0.4%) | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 15. | ALA3760750 | F | Antiobesity activity in DIO C57BL/6 mouse assessed as decrease in abdominal fat content at 2.2 mg/kg, sc administered every 4 days for 21 days (Rvb = 8.1 +/- 0.4%) | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 16. | ALA3760751 | F | Antiobesity activity in DIO C57BL/6 mouse assessed as decrease in abdominal fat content at 2.2 mg/kg, sc administered every 7 days for 21 days (Rvb = 8.1 +/- 0.4%) | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 17. | ALA3760755 | A | Drug uptake in DIO C57BL/6 mouse plasma at 2.2 mg/kg, sc administered every 2 days for 28 days by LC/MS analysis | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 18. | ALA3760756 | A | Drug uptake in DIO C57BL/6 mouse liver at 2.2 mg/kg, sc administered every 2 days for 28 days by LC/MS analysis | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 19. | ALA3760757 | A | Drug uptake in DIO C57BL/6 mouse lung at 2.2 mg/kg, sc administered every 2 days for 28 days by LC/MS analysis | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature | |
| 20. | ALA3760758 | A | Drug uptake in DIO C57BL/6 mouse kidney at 2.2 mg/kg, sc administered every 2 days for 28 days by LC/MS analysis | Mus musculus | 1 | ALA3758116 | organism-based format | Scientific Literature |
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