#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3760352	B	Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment preincubated for 30 mins followed by CP55,940 addition measured for 90 mins by PathHunter assay	Homo sapiens	9	ALA3758125	cell-based format	Scientific Literature
2.	ALA3760353	B	Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced beta-arrestin recruitment preincubated for 30 mins followed by CP55,940 addition measured for 90 mins by PathHunter assay relative to control	Homo sapiens	9	ALA3758125	cell-based format	Scientific Literature
3.	ALA3760354	F	Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced cAMP accumulation preincubated for 30 mins followed by CP55,940 addition measured for 30 mins by HitHunter assay	Homo sapiens	9	ALA3758125	cell-based format	Scientific Literature
4.	ALA3760355	F	Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assessed as effect on CP55,940-induced inhibition of forskolin-induced cAMP accumulation preincubated for 30 mins followed by CP55,940 addition measured for 30 mins by HitHunter assay relative to control	Homo sapiens	9	ALA3758125	cell-based format	Scientific Literature
5.	ALA3760356	F	Negative allosteric modulator activity at CB1R in mouse brain membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding at 100 nM and 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
6.	ALA3760357	F	Agonist activity at CB1R in mouse brain membranes assessed as [35S]GTPgammaS binding at 100 nM and 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
7.	ALA3760358	F	Inverse agonist activity at CB1R in mouse brain membranes assessed as [35S]GTPgammaS binding at 100 nM and 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
8.	ALA3760359	F	Agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding up to 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Homo sapiens	1	ALA3758125	cell-based format	Scientific Literature
9.	ALA3760360	F	Inverse agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition [35S]GTPgammaS binding up to 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Homo sapiens	1	ALA3758125	cell-based format	Scientific Literature
10.	ALA3760363	B	Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scintillation spectrometric analysis	Homo sapiens	3	ALA3758125	cell-based format	Scientific Literature
11.	ALA3760364	F	Negative allosteric modulator activity at CB1R in mouse brain membranes assessed as Emax for CP55,940-induced [35S]GTPgammaS binding at 100 nM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis relative to control (Rvb = 94.3%)	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
12.	ALA3760365	F	Negative allosteric modulator activity at CB1R in mouse brain membranes assessed as Emax for CP55,940-induced [35S]GTPgammaS binding at 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis relative to control (Rvb = 94.3%)	Mus musculus	2	ALA3758125	cell membrane format	Scientific Literature
13.	ALA3760366	F	Activity at CB1R in mouse brain membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
14.	ALA3760367	F	Activity at CB1R in mouse brain membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding at 100 nM and 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis relative to control	Mus musculus	1	ALA3758125	cell membrane format	Scientific Literature
15.	ALA3760368	B	Positive allosteric modulator activity at human CB1R expressed in CHO cells assessed as enhanced binding of [3H]CP55,940 after 60 mins by liquid scintillation spectrometric analysis relative to control	Homo sapiens	3	ALA3758125	cell-based format	Scientific Literature
16.	ALA3760369	B	Positive allosteric modulator activity at human CB1R expressed in HEK293 cell membranes assessed as enhanced binding of [3H]CP55,940 at 500 nM by liquid scintillation spectrometric analysis	Homo sapiens	1	ALA3758125	cell-based format	Scientific Literature
17.	ALA3760370	F	Selectivity index, ratio of EC50 for human CB1R by cAMP assay to EC50 for human CB1R by beta-arrestin recruitment assay	Homo sapiens	7	ALA3758125	single protein format	Scientific Literature
18.	ALA3760371	B	Positive allosteric modulator activity at human CB1R expressed in HEK293 cell membranes assessed as enhanced specific binding of [3H]CP55,940 at 500 nM pre-incubated for 60 mins before [3H]CP55,940 addition followed by drug wash-out by liquid scintillation spectrometric-based saturation binding assay	Homo sapiens	2	ALA3758125	cell-based format	Scientific Literature
19.	ALA3760372	B	Activity at human CB1R expressed in HEK293 cell membranes assessed as reduction in binding of [3H]CP55,940 at 500 nM after 90 to 120 mins by liquid scintillation spectrometric analysis	Homo sapiens	1	ALA3758125	cell-based format	Scientific Literature