# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3761788 | B | Potency index, ratio of SAHA IC50 to compound IC50 for inhibition of human recombinant HDAC1 | Homo sapiens | 1 | ALA3758132 | single protein format | Scientific Literature | |
2. | ALA3761789 | B | Potency index, ratio of SAHA IC50 to compound IC50 for inhibition of human recombinant HDAC2 | Homo sapiens | 1 | ALA3758132 | single protein format | Scientific Literature | |
3. | ALA3761790 | B | Potency index, ratio of SAHA IC50 to compound IC50 for inhibition of human recombinant HDAC3 | Homo sapiens | 1 | ALA3758132 | single protein format | Scientific Literature | |
4. | ALA3761791 | B | Inhibition of human recombinant HDAC1 using acetyllysine tripeptide coupled with 7-amino-4-methylcoumarin as substrate by fluorescence assay | Homo sapiens | 12 | ALA3758132 | single protein format | Scientific Literature | |
5. | ALA3761792 | B | Inhibition of human recombinant HDAC2 using acetyllysine tripeptide coupled with 7-amino-4-methylcoumarin as substrate by fluorescence assay | Homo sapiens | 12 | ALA3758132 | single protein format | Scientific Literature | |
6. | ALA3761793 | B | Inhibition of human recombinant HDAC3 using acetyllysine tripeptide coupled with 7-amino-4-methylcoumarin as substrate by fluorescence assay | Homo sapiens | 12 | ALA3758132 | single protein format | Scientific Literature | |
7. | ALA3761794 | B | Inhibition of HDAC in mouse forebrain primary neurons assessed as acetylation of histone H3K9 after 24 hrs by immunofluorescence assay | Mus musculus | 3 | ALA3758132 | assay format | Scientific Literature | |
8. | ALA3762334 | A | Cmax in C57BL/6 mouse brain at 25 mg/kg, ip after 0.5 hrs by LC/MS/MS analysis | Mus musculus | 2 | ALA3758132 | organism-based format | Scientific Literature | |
9. | ALA3762492 | B | Inhibition of human recombinant HDAC6 using acetyllysine tripeptide coupled with 7-amino-4-methylcoumarin as substrate by fluorescence assay | Homo sapiens | 2 | ALA3758132 | single protein format | Scientific Literature | |
10. | ALA3762493 | B | Inhibition of human recombinant HDAC5 using acetyllysine tripeptide coupled with 7-amino-4-methylcoumarin as substrate by fluorescence assay | Homo sapiens | 2 | ALA3758132 | single protein format | Scientific Literature | |
11. | ALA4014727 | B | Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assay | Schistosoma mansoni | 168 | ALA4014283 | single protein format | Scientific Literature |