# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3762124 | A | Plasma clearance in iv dosed rat | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
2. | ALA3762125 | A | Efflux ratio of permeability from basolateral to apical side over apical to basolateral side in MDCK cells | Canis lupus familiaris | 7 | cell-based format | Scientific Literature | ||
3. | ALA3762126 | A | Apparent permeability from the apical to basolateral side in MDCK cells | Canis lupus familiaris | 7 | cell-based format | Scientific Literature | ||
4. | ALA3762127 | B | Inhibition of EGFR T790M/L858R mutant (unknown origin) | Homo sapiens | 30 | protein format | Scientific Literature | ||
5. | ALA3762128 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
6. | ALA3762129 | A | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
7. | ALA3762130 | A | Total AUC in rat at 5 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
8. | ALA3762131 | A | Unbound AUC in rat at 5 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
9. | ALA3762135 | B | Inhibition of Hyl (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3762136 | B | Inhibition of wild type EGFR (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
11. | ALA3762137 | B | Inhibition of EGFR L858R mutant (unknown origin) | Homo sapiens | 5 | protein format | Scientific Literature | ||
12. | ALA3762138 | B | Inhibition of EGFR deletion (746 to 750 residues) mutant (unknown origin) | Homo sapiens | 5 | protein format | Scientific Literature | ||
13. | ALA3762139 | B | Inhibition of EGFR T790M/deletion (746 to 750 residues) mutant (unknown origin) | Homo sapiens | 6 | protein format | Scientific Literature | ||
14. | ALA3762140 | B | Inhibition of ACVR1B (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA3762141 | B | Inhibition of ACVR2B (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA3762142 | B | Inhibition of AKT1 (unknown origin) at 100 nM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA3762143 | B | Inhibition of AKT2 (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA3762144 | B | Inhibition of AKT3 (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA3762145 | B | Inhibition of ALK2 (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA3762146 | B | Inhibition of ARK5 (unknown origin) at 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature |