# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3760805 | B | Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 mins followed by substrate addition by HPLC-MS analysis | Homo sapiens | 44 | ALA3758149 | single protein format | Scientific Literature | |
2. | ALA3760807 | B | Inhibition of recombinant human MAO-A after 60 mins MAO-glo assay | Homo sapiens | 5 | ALA3758149 | single protein format | Scientific Literature | |
3. | ALA3760808 | B | Inhibition of recombinant human MAO-B after 60 mins MAO-glo assay | Homo sapiens | 5 | ALA3758149 | single protein format | Scientific Literature | |
4. | ALA3760809 | B | Selectivity index, ratio of Ki for recombinant human MAO-B to Ki for recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) | Homo sapiens | 4 | ALA3758149 | assay format | Scientific Literature | |
5. | ALA3760810 | B | Inhibition of recombinant human AKT for 60 mins by ELISA | Homo sapiens | 1 | ALA3758149 | single protein format | Scientific Literature | |
6. | ALA3760811 | B | Inhibition of LSD1 in human MV4-11 cells assessed as increase in H3K4me2 level at 1 uM after 3 days by Western blot analysis | Homo sapiens | 1 | ALA3758149 | cell-based format | Scientific Literature | |
7. | ALA3760813 | F | Antiproliferative activity against human MV4-11 cells by XTT assay | Homo sapiens | 6 | ALA3758149 | cell-based format | Scientific Literature | |
8. | ALA3760814 | F | Antiproliferative activity against human MOLM13 cells by XTT assay | Homo sapiens | 6 | ALA3758149 | cell-based format | Scientific Literature | |
9. | ALA3760815 | F | Antiproliferative activity against human MCF7 cells by XTT assay | Homo sapiens | 6 | ALA3758149 | cell-based format | Scientific Literature | |
10. | ALA3760816 | F | Antiproliferative activity against human MDA-MB-231 cells by XTT assay | Homo sapiens | 6 | ALA3758149 | cell-based format | Scientific Literature | |
11. | ALA3760817 | A | Antiproliferative activity against human WI38 cells by MTT assay | Homo sapiens | 6 | ALA3758149 | cell-based format | Scientific Literature | |
12. | ALA4042251 | B | Inhibition of LSD1 (unknown origin) | Homo sapiens | 5 | ALA4041507 | single protein format | Scientific Literature | |
13. | ALA4826336 | B | Inhibition of human recombinant LSD1 by horseradish peroxidase-coupled fluorometric assay | Homo sapiens | 40 | ALA4825677 | single protein format | Scientific Literature | |
14. | ALA4826340 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
15. | ALA4826341 | F | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
16. | ALA4826342 | F | Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
17. | ALA4826343 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
18. | ALA4826344 | F | Antiproliferative activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
19. | ALA4826345 | A | Cytotoxicity against human THLE-2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
20. | ALA4826346 | A | Metabolic stability in human liver microsomes assessed as half-life by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature |