| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3761528 | B | Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addition by beta counting analysis | Homo sapiens | 14 | ALA3758078 | cell-based format | Scientific Literature | |
| 2. | ALA3761529 | B | Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioligand addition by gamma counting analysis | Rattus norvegicus | 14 | ALA3758078 | cell membrane format | Scientific Literature | |
| 3. | ALA3761530 | B | Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by radioligand addition by gamma counting analysis | Rattus norvegicus | 15 | ALA3758078 | cell membrane format | Scientific Literature | |
| 4. | ALA3761532 | B | Selectivity ratio of Ki for rat alpha4beta2 nACh receptor to Ki for human alpha3beta4 nACh receptor | Homo sapiens | 15 | ALA3758078 | assay format | Scientific Literature | |
| 5. | ALA3761533 | B | Selectivity ratio of Ki for rat alpha7 nACh receptor to Ki for human alpha3beta4 nACh receptor | Homo sapiens | 15 | ALA3758078 | assay format | Scientific Literature | |
| 6. | ALA3761536 | B | Agonist activity at human alpha7 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patch clamp assay | Homo sapiens | 1 | ALA3758078 | cell-based format | Scientific Literature | |
| 7. | ALA3761539 | B | Agonist activity at human alpha3beta4 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patch clamp assay | Homo sapiens | 1 | ALA3758078 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!