| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3761528 | B | Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addition by beta counting analysis | Homo sapiens | 14 | ALA3758078 | cell-based format | Scientific Literature | |
| 2. | ALA3761529 | B | Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioligand addition by gamma counting analysis | Rattus norvegicus | 14 | ALA3758078 | cell membrane format | Scientific Literature | |
| 3. | ALA3761530 | B | Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by radioligand addition by gamma counting analysis | Rattus norvegicus | 15 | ALA3758078 | cell membrane format | Scientific Literature | |
| 4. | ALA3761532 | B | Selectivity ratio of Ki for rat alpha4beta2 nACh receptor to Ki for human alpha3beta4 nACh receptor | Homo sapiens | 15 | ALA3758078 | assay format | Scientific Literature | |
| 5. | ALA3761533 | B | Selectivity ratio of Ki for rat alpha7 nACh receptor to Ki for human alpha3beta4 nACh receptor | Homo sapiens | 15 | ALA3758078 | assay format | Scientific Literature | |
| 6. | ALA3761537 | B | Agonist activity at human alpha4beta2 nACh receptor expressed in rat GHC41 cells assessed as increase in current amplitudes at 0.1 to 100 uM after 2 to 3 days by patch clamp assay | Homo sapiens | 1 | ALA3758078 | cell-based format | Scientific Literature | |
| 7. | ALA3761538 | B | Agonist activity at human alpha3beta4 nACh receptor expressed in rat GHC41 cells assessed as increase in current amplitudes at 0.1 to 100 uM after 2 to 3 days by patch clamp assay relative to acetylcholine | Homo sapiens | 1 | ALA3758078 | cell-based format | Scientific Literature | |
| 8. | ALA3761540 | B | Agonist activity at human alpha7 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes at 0.1 to 100 uM after 2 to 3 days by patch clamp assay | Homo sapiens | 1 | ALA3758078 | cell-based format | Scientific Literature | |
| 9. | ALA3761541 | B | Antagonist activity at human alpha4beta2 nACh receptor | Homo sapiens | 2 | ALA3758078 | protein complex format | Scientific Literature | |
| 10. | ALA3761542 | B | Antagonist activity at human alpha3beta4 nACh receptor | Homo sapiens | 2 | ALA3758078 | protein complex format | Scientific Literature |
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