| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3762431 | Functional | Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization | Homo sapiens | 46 | ALA3758107 | cell-based format | Scientific Literature | |
| 2. | ALA3762432 | Functional | Positive allosteric modulation of human mGlu1 receptor at 10 uM by cell based calcium mobilization relative to glutamate | Homo sapiens | 57 | ALA3758107 | cell-based format | Scientific Literature | |
| 3. | ALA3762436 | ADME | Clearance in human hepatocytes | Homo sapiens | 5 | ALA3758107 | cell-based format | Scientific Literature | |
| 4. | ALA3762437 | ADME | Clearance in rat hepatocytes | Rattus norvegicus | 5 | ALA3758107 | cell-based format | Scientific Literature | |
| 5. | ALA3762438 | ADME | Fraction unbound in human plasma by rapid equilibrium dialysis binding assay | Homo sapiens | 5 | ALA3758107 | cell-free format | Scientific Literature | |
| 6. | ALA3762439 | ADME | Fraction unbound in rat plasma by rapid equilibrium dialysis binding assay | Rattus norvegicus | 5 | ALA3758107 | cell-free format | Scientific Literature | |
| 7. | ALA3762440 | ADME | Fraction unbound in rat brain by rapid equilibrium dialysis binding assay | Rattus norvegicus | 5 | ALA3758107 | tissue-based format | Scientific Literature | |
| 8. | ALA3762441 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 5 | ALA3758107 | single protein format | Scientific Literature | |
| 9. | ALA3762442 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 5 | ALA3758107 | single protein format | Scientific Literature | |
| 10. | ALA3762443 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 5 | ALA3758107 | single protein format | Scientific Literature | |
| 11. | ALA3762444 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 5 | ALA3758107 | single protein format | Scientific Literature | |
| 12. | ALA3762445 | ADME | Half life in rat at 0.25 mg/kg, iv | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 13. | ALA3762446 | ADME | Mean residence time in rat at 0.25 mg/kg, iv | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 14. | ALA3762447 | ADME | Plasma clearance in rat at 0.25 mg/kg, iv | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 15. | ALA3762448 | ADME | Volume of distribution at steady state in rat at 0.25 mg/kg, iv | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 16. | ALA3762449 | ADME | Plasma concentration in rat at 0.25 mg/kg, iv by PBL cassette study | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 17. | ALA3762450 | ADME | Drug level in rat brain at 0.25 mg/kg, iv by PBL cassette study | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 18. | ALA3762451 | ADME | Ratio of drug level in brain to plasma in rat brain at 0.25 mg/kg, iv after 0.25 hrs by PBL cassette study | Rattus norvegicus | 5 | ALA3758107 | organism-based format | Scientific Literature | |
| 19. | ALA3762452 | Functional | Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilization | Homo sapiens | 5 | ALA3758107 | cell-based format | Scientific Literature | |
| 20. | ALA3762453 | Binding | Selectivity ratio of EC50 for human mGlu5 receptor to EC50 for human mGlu1 receptor | Homo sapiens | 5 | ALA3758107 | assay format | Scientific Literature |
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