| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3768070 | A | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in pig LLC-PK cells expressing rat MDR1a | Sus scrofa | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 2. | ALA3768071 | A | Fraction unbound in human plasma | Homo sapiens | 1 | ALA3763140 | cell-free format | Scientific Literature | |
| 3. | ALA3768072 | A | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in pig LLC-PK cells expressing human MDR1a | Sus scrofa | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 4. | ALA3769212 | A | Apparent permeability across pig LLC-PK cells expressing human/rat MDR1a | Sus scrofa | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 5. | ALA3769213 | B | Positive allosteric modulation of 5-HT2B receptor (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 6. | ALA3769214 | B | Positive allosteric modulation of platelet-activating factor receptor (unknown origin) | Homo sapiens | 1 | ALA3763140 | assay format | Scientific Literature | |
| 7. | ALA3769215 | B | Positive allosteric modulation of mGluR6 (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 8. | ALA3769216 | B | Positive allosteric modulation of mGluR5 (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 9. | ALA3769217 | B | Positive allosteric modulation of mGluR4 (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 10. | ALA3769218 | B | Positive allosteric modulation of mGluR3 (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 11. | ALA3769219 | B | Partial agonist activity at rat mGluR2 at 10 uM | Rattus norvegicus | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 12. | ALA3769220 | B | Partial agonist activity at human mGluR2 at 10 uM | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 13. | ALA3769221 | B | Positive allosteric modulation of rat mGluR2 by GTP-gamma-S binding assay | Rattus norvegicus | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 14. | ALA3769222 | B | Positive allosteric modulation of human mGluR2 by GTP-gamma-S binding assay | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
| 15. | ALA3769223 | B | Positive allosteric modulation of human mGluR2 expressed in CHO cells assessed as increase in glutamate EC50 at 10 uM preincubated for 5 mins followed by glutamate addition for 3 mins by FLIPR assay relative to control | Homo sapiens | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 16. | ALA3769224 | B | Positive allosteric modulation of human mGluR2 expressed in CHO cells assessed as increase in glutamate EC50 at 1 uM preincubated for 5 mins followed by glutamate addition for 3 mins by FLIPR assay relative to control | Homo sapiens | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 17. | ALA3769225 | B | Positive allosteric modulation of human mGluR2 expressed in CHO cells assessed as increase in glutamate EC50 at 0.1 uM preincubated for 5 mins followed by glutamate addition for 3 mins by FLIPR assay relative to control | Homo sapiens | 1 | ALA3763140 | cell-based format | Scientific Literature | |
| 18. | ALA3766106 | B | Positive allosteric modulation of recombinant human mGluR2 expressed in CHO cells preincubated for 5 mins followed by stimulation with EC20 concentration of glutamate for 3 mins by FLIPR assay | Homo sapiens | 20 | ALA3763140 | cell-based format | Scientific Literature | |
| 19. | ALA3766107 | P | Solubility of compound at pH 7 | 17 | ALA3763140 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA3766108 | B | Displacement of [35S]MK-499 from human ERG expressed in HEK293 cell membranes after 75 mins | Homo sapiens | 3 | ALA3763140 | cell-based format | Scientific Literature |
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