# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3767148 | B | Inhibition of IKKbeta (unknown origin) at 10 uM by TR-FRET assay | Homo sapiens | 17 | single protein format | Scientific Literature | ||
2. | ALA3767149 | B | Inhibition of IKKbeta (unknown origin) by TR-FRET assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
3. | ALA3767150 | B | Inhibition of IKKbeta (unknown origin) transfected in human HeLa cells assessed as inhibition of TPA-induced NF-kappaB activation at 10 uM pre-incubated with compound for 1 hr followed by TPA addition after 8 hrs by luciferase reporter gene assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
4. | ALA3767151 | B | Inhibition of IKKbeta in primary type-2 collagen immunized mouse splenocytes assessed as inhibition of TNFalpha production at 10 uM after 72 hrs by ELISA | Mus musculus | 13 | assay format | Scientific Literature | ||
5. | ALA3767152 | A | Metabolic stability in rat plasma assessed as compound remaining after 120 mins | Rattus norvegicus | 8 | cell-free format | Scientific Literature | ||
6. | ALA3767153 | A | Half life in human microsomes | Homo sapiens | 8 | assay format | Scientific Literature |