# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3769127 | Binding | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assay | Homo sapiens | 20 | ALA3763032 | single protein format | Scientific Literature | |
2. | ALA3769128 | ADME | Cytotoxicity against human MCF12A cells after 72 hrs by CyQuant cell proliferation assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
3. | ALA3769129 | Functional | Cytotoxicity against human MDA-MB-468 cells expressing ChoKalpha after 72 hrs by CyQuant cell proliferation assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
4. | ALA3769130 | Functional | Cytotoxicity against human MDA-MB-415 cells expressing ChoKalpha after 72 hrs by CyQuant cell proliferation assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
5. | ALA3769131 | Binding | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) assessed as ligand residence time by surface plasmon resonance assay | Homo sapiens | 7 | ALA3763032 | single protein format | Scientific Literature | |
6. | ALA3769132 | Binding | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) assessed as association rate constant by surface plasmon resonance assay | Homo sapiens | 7 | ALA3763032 | single protein format | Scientific Literature | |
7. | ALA3769133 | Binding | Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled ATP regeneration assay | Homo sapiens | 20 | ALA3763032 | single protein format | Scientific Literature | |
8. | ALA3769134 | ADME | Cytotoxicity against human MCF10A cells after 72 hrs by CyQuant cell proliferation assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
9. | ALA3769135 | Functional | Induction of apoptosis in human MDA-MB-415 cells expressing ChoKalpha after 24 hrs by caspase-3/7 assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
10. | ALA3769136 | ADME | Induction of apoptosis in human MCF12A cells upto 40 uM after 24 hrs by caspase-3/7 assay | Homo sapiens | 2 | ALA3763032 | cell-based format | Scientific Literature | |
11. | ALA3766470 | Binding | Inhibition of ChoKalpha in human MDA-MB-415 cells assessed as reduction in phosphocholine level after 24 hrs by NMR analysis | Homo sapiens | 1 | ALA3763032 | cell-based format | Scientific Literature | |
12. | ALA3766471 | ADME | Effect on phosphocholine level in human MCF12A cells after 24 hrs by NMR analysis | Homo sapiens | 1 | ALA3763032 | cell-based format | Scientific Literature |