# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA648496 | B | Displacement of ivermectin from avermectin receptor of Caenorhabditis elegans | Caenorhabditis elegans | 14 | ALA1124629 | assay format | Scientific Literature | |
2. | ALA882854 | F | Antiparasitic activity against southern army worm Spodoptera eridania | Spodoptera eridania | 10 | ALA1124629 | organism-based format | Scientific Literature | |
3. | ALA811436 | F | Antiparasitic activity against two-spotted spider mite Tetranychus urticae on bean plants | Tetranychus urticae | 14 | ALA1124629 | organism-based format | Scientific Literature | |
4. | ALA1001103 | F | Antileishmanial activity against GFP-tagged Leishmania amazonensis Josefa promastigotes after 72 hrs by fluorimetric assay | Leishmania amazonensis | 14 | ALA1140890 | organism-based format | Scientific Literature | |
5. | ALA1001104 | F | Antileishmanial activity against GFP-tagged Leishmania amazonensis Josefa amastigotes infected in mouse peritoneal macrophages after 72 hrs by fluorimetric assay | Leishmania amazonensis | 14 | ALA1140890 | organism-based format | Scientific Literature | |
6. | ALA1001105 | A | Cytotoxicity against mouse peritoneal macrophages assessed as LDH release after 48 hrs | Mus musculus | 14 | ALA1140890 | cell-based format | Scientific Literature | |
7. | ALA1001106 | U | Selectivity index, ratio of IC50 for mouse peritoneal macrophages to IC50 for Leishmania amazonensis Josefa amastigotes | 14 | ALA1140890 | assay format | Scientific Literature | ||
8. | ALA4358319 | F | Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in human HuH7 cells assessed as reduction in parasite load at 1 to 10 uM preincubated for 1 hr followed by parasite infection and measured after 46 hrs by bioluminescence assay | Plasmodium berghei | 5 | ALA4354848 | organism-based format | Scientific Literature | |
9. | ALA4358320 | F | Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in human HuH7 cells assessed as reduction in parasite load preincubated for 1 hr followed by parasite infection and measured after 46 hrs by bioluminescence assay | Plasmodium berghei | 6 | ALA4354848 | organism-based format | Scientific Literature | |
10. | ALA4358321 | A | Cytotoxicity against human HuH7 cells infected with luciferase expressing Plasmodium berghei sporozoites assessed as reduction in cell viability preincubated for 1 hr followed by parasite infection and measured after 48 hrs by alamar blue assay | Homo sapiens | 5 | ALA4354848 | cell-based format | Scientific Literature | |
11. | ALA4358323 | F | Antiplasmodial activity against chloroquine-sensitive ring-stage synchronized cultures of Plasmodium falciparum NF54 incubated for 48 hrs by SYBR green I dye based flow cytometry | Plasmodium falciparum | 6 | ALA4354848 | organism-based format | Scientific Literature | |
12. | ALA4358325 | F | Insecticidal activity against compound treated Balb/c mouse blood fed Anopheles stephensi assessed as effect on mosquito survival at 1 mg/kg, po administered via gavage 24 hrs prior to blood feed for 20 mins under dark condition and measured daily up to 14 days post blood feed | Anopheles stephensi | 3 | ALA4354848 | organism-based format | Scientific Literature |