# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3768327 | B | Binding affinity to LRP6 in human SH-SY5Y cells assessed as DKK1/LRP6 interaction-mediated increase in beta-catenin level at 10 uM incubated for 1 hr using compound pre-treated DKK1 conditioned media by Western blot analysis | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA3768328 | B | Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned media after 2 hrs by fluorescence microscopic analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA3768329 | A | Cytotoxicity against human SH-SY5Y cells at 10 to 100 uM after 24 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
4. | ALA3768330 | B | Binding affinity to LRP6 in human SH-SY5Y cells assessed as inhibition of DKK1/LRP6 interaction-mediated tau phosphorylation at serine 396 at 10 uM incubated for 1 hr using compound pre-treated DKK1 conditioned media by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |