| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3769181 | A | Activity at porcine leucine aminopeptidase by HPLC analysis | Sus scrofa | 13 | ALA3763088 | single protein format | Scientific Literature | |
| 2. | ALA3769182 | A | Prodrug conversion assessed as porcine leucine aminopeptidase-mediated compound cleavage by HPLC analysis | Sus scrofa | 13 | ALA3763088 | single protein format | Scientific Literature | |
| 3. | ALA3766075 | F | Cytotoxicity against human SKOV3 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 25 | ALA3763088 | cell-based format | Scientific Literature | |
| 4. | ALA3766076 | F | Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 25 | ALA3763088 | cell-based format | Scientific Literature | |
| 5. | ALA3766077 | F | Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay | Homo sapiens | 25 | ALA3763088 | cell-based format | Scientific Literature | |
| 6. | ALA3766090 | F | Induction of tumor-specific vascular damage in luciferase expressing human MDA-MB-231 cells xenografted in SCID mouse assessed as reduction in light emission at 15 mg/kg at 4 hrs post dose by bioluminescence imaging assay (Rvb = 22%) | Homo sapiens | 1 | ALA3763088 | organism-based format | Scientific Literature | |
| 7. | ALA3766091 | F | Induction of tumor-specific vascular damage in luciferase expressing human MDA-MB-231 cells xenografted in SCID mouse assessed as reduction in light emission at 15 mg/kg at 24 hrs post dose by bioluminescence imaging assay (Rvb = 24%) | Homo sapiens | 1 | ALA3763088 | organism-based format | Scientific Literature | |
| 8. | ALA3766092 | F | Induction of tumor-specific vascular damage in luciferase expressing human MDA-MB-231 cells xenografted in SCID mouse assessed as reduction in light emission at 10 mg/kg at 4 hrs post dose by bioluminescence imaging assay (Rvb = 22%) | Homo sapiens | 1 | ALA3763088 | organism-based format | Scientific Literature | |
| 9. | ALA3766093 | F | Induction of tumor-specific vascular damage in luciferase expressing human MDA-MB-231 cells xenografted in SCID mouse assessed as reduction in light emission at 10 mg/kg at 24 hrs post dose by bioluminescence imaging assay (Rvb = 24%) | Homo sapiens | 1 | ALA3763088 | organism-based format | Scientific Literature |
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