| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3767264 | B | Antagonist activity at human AKT1-PH domain (1 to 121 residues) assessed as reduction of AKT1-PH interaction with PC/PE/PS/PI(3,4,5)P3 at 50 uM after 30 mins by competitive SPR analysis relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA3767265 | B | Antagonist activity at mouse GRP1-PH domain (1 to 127 residues) assessed as reduction in PI(3,4,5)P3/GRP1-PH interaction at 50 uM after 30 mins by competitive SPR analysis relative to control | Mus musculus | 4 | single protein format | Scientific Literature | ||
| 3. | ALA3767267 | B | Antagonist activity at human AKT1-PH domain (1 to 121 residues) assessed as reduction of AKT1-PH interaction with PC/PE/PS/PI(3,4,5)P3 after 30 mins by competitive SPR analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA3767268 | B | Antagonist activity at mouse GRP1-PH domain (1 to 127 residues) assessed as reduction in PI(3,4,5)P3/GRP1-PH interaction after 30 mins by competitive SPR analysis | Mus musculus | 4 | single protein format | Scientific Literature | ||
| 5. | ALA3767426 | A | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation at 1 to 100 uM after 48 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA3767428 | A | Effect on membrane fluidity in PC/PE/PS liposome assessed as DPH probe anisotropy changes at 15 uM incubated for 30 mins by fluorescence anisotropic analysis | 5 | assay format | Scientific Literature | |||
| 7. | ALA3767429 | A | Effect on membrane fluidity in PC/PE/PS liposome assessed as NBD-PE probe anisotropy changes at 15 uM incubated for 30 mins by fluorescence anisotropic analysis | 5 | assay format | Scientific Literature |
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