| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3767197 | B | Inhibition of recombinant His-tagged human SK1 assessed as production of [32P]-S1P using sphingosine as substrate at 10 uM by TLC method in presence of 100 uM [gamma32P]-ATP relative to control | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 2. | ALA3767198 | B | Inhibition of recombinant human SK2 assessed as production of [32P] S1P using sphingosine as substrate at 10 uM by TLC method in presence of 100 uM [gamma32P]-ATP relative to control | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 3. | ALA3767199 | F | Antiproliferative activity against human PC3 cells after 72 hrs by MTS assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 4. | ALA3767200 | F | Induction of SK1 degradation in HEK293 cells at 10 uM after 16 hrs by western blotting analysis in presence of proteasome inhibitor MG132 | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA3767203 | B | Inhibition of Des1 activity in human Jurkat cells using fluorescence labeled DhCer-C6-NBD as substrate at 1 and 10 uM after 3 hrs by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3767204 | F | Increase in total dhCer level in human PC3 cells at 10 uM after 5 hrs by LC-MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3767205 | F | Increase in total Cer level in human PC3 cells at 10 uM after 5 hrs by LC-MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3767206 | F | Increase in total Sph level in human PC3 cells at 10 uM after 5 hrs by LC-MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3767355 | F | Increase in total S1P level in human PC3 cells at 10 uM after 5 hrs by LC-MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3767356 | F | Effect on total dhCer level in human PC3 cells at 1 uM after 5 hrs by LC-MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3767357 | F | Anticlonogenic activity against human PC3 cells after 21 days by soft agar colony forming assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3767360 | F | Anticlonogenic activity against human PC3 cells after 21 days by plate assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3767361 | F | Anticlonogenic activity against human PC3 cells at 0.05 to 10 uM after 21 days by soft agar colony forming assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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