#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3766477	B	Inhibition of recombinant human TYK2 kinase domain (885-1176 residues) using Ulight-JAK1 substrate peptide assessed as reduction in ATP-dependent substrate phosphorylation after 45 mins by TR-FRET assay	Homo sapiens	20	ALA3763089	single protein format	Scientific Literature
2.	ALA3766652	B	Inhibition of JAK1 (unknown origin) using Ulight-JAK1 substrate peptide assessed as reduction in ATP-dependent substrate phosphorylation after 45 mins by TR-FRET assay	Homo sapiens	20	ALA3763089	single protein format	Scientific Literature
3.	ALA3766653	B	Inhibition of JAK2 (unknown origin) using Ulight-JAK1 substrate peptide assessed as reduction in ATP-dependent substrate phosphorylation after 45 mins by TR-FRET assay	Homo sapiens	20	ALA3763089	single protein format	Scientific Literature
4.	ALA3766654	B	Inhibition of JAK3 (unknown origin) using Ulight-JAK1 substrate peptide assessed as reduction in ATP-dependent substrate phosphorylation after 45 mins by TR-FRET assay	Homo sapiens	20	ALA3763089	single protein format	Scientific Literature
5.	ALA3766655	B	Selectivity ratio of IC50 for JAK1 (unknown origin) to IC50 for recombinant human TYK2 kinase domain (885-1176 residues)	Homo sapiens	16	ALA3763089	assay format	Scientific Literature
6.	ALA3766656	B	Selectivity ratio of IC50 for JAK2 (unknown origin) to IC50 for recombinant human TYK2 kinase domain (885-1176 residues)	Homo sapiens	16	ALA3763089	assay format	Scientific Literature
7.	ALA3766657	B	Selectivity ratio of IC50 for JAK3 (unknown origin) to IC50 for recombinant human TYK2 kinase domain (885-1176 residues)	Homo sapiens	16	ALA3763089	assay format	Scientific Literature
8.	ALA3766658	B	Inhibition of TYK2/JAK2 in human PBMC assessed as reduction in IL-23-induced STAT4 phosphorylation preincubated for 5 mins followed by IL-23 stimulation for 15 to 60 mins by flow cytometry analysis	Homo sapiens	2	ALA3763089	protein complex format	Scientific Literature
9.	ALA3766659	B	Inhibition of TYK2 in human Jurkat cells assessed as reduction in IL-23-induced luciferase gene expression after 24 hrs	Homo sapiens	12	ALA3763089	cell-based format	Scientific Literature
10.	ALA3766660	A	Clearance in rat at 0.1 mg/kg, iv	Rattus norvegicus	4	ALA3763089	organism-based format	Scientific Literature
11.	ALA3766661	A	Cmax in rat at 1 mg/kg, po	Rattus norvegicus	4	ALA3763089	organism-based format	Scientific Literature
12.	ALA3766662	A	Mean residence time in rat at 1 mg/kg, po	Rattus norvegicus	4	ALA3763089	organism-based format	Scientific Literature
13.	ALA3766663	A	AUC in rat at 1 mg/kg, po	Rattus norvegicus	4	ALA3763089	organism-based format	Scientific Literature
14.	ALA3766664	A	Oral bioavailability in rat at 1 mg/kg	Rattus norvegicus	4	ALA3763089	organism-based format	Scientific Literature
15.	ALA3766665	F	Inhibition of IL-23-induced IL-22 production in po dosed Lewis rat ear administered 30 mins prior to IL-23 injection measured after 24 hrs by ELISA	Rattus norvegicus	1	ALA3763089	organism-based format	Scientific Literature
16.	ALA3766666	B	Inhibition of TYK2/JAK1 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation preincubated for 5 mins followed by IFNalpha stimulation for 15 to 60 mins by flow cytometry analysis	Homo sapiens	2	ALA3763089	protein complex format	Scientific Literature
17.	ALA3766667	B	Inhibition of JAK1/JAK2/TYK2 in human PBMC assessed as reduction in IL-6-induced STAT1 phosphorylation preincubated for 5 mins followed by IL-6 stimulation for 15 to 60 mins by flow cytometry analysis	Homo sapiens	2	ALA3763089	protein complex format	Scientific Literature
18.	ALA3766668	B	Inhibition of JAK1/JAK3 in human PBMC assessed as reduction in IL-21-induced STAT3 phosphorylation preincubated for 5 mins followed by IL-21 stimulation for 15 to 60 mins by flow cytometry analysis	Homo sapiens	2	ALA3763089	protein complex format	Scientific Literature
19.	ALA3766669	B	Inhibition of JAK2 in human PBMC assessed as reduction in GM-CSF-induced STAT5 phosphorylation preincubated for 5 mins followed by GM-CSF stimulation for 15 to 60 mins by flow cytometry analysis	Homo sapiens	2	ALA3763089	single protein format	Scientific Literature
20.	ALA3766670	B	Selectivity ratio of IC50 for JAK2 in human PBMC assessed as reduction in GM-CSF-induced STAT5 phosphorylation to IC50 for TYK2/JAK2 in human PBMC assessed as reduction in IL-23-induced STAT4 phosphorylation	Homo sapiens	1	ALA3763089	assay format	Scientific Literature