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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3767595 F Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in presence of 40% serum relative to (R)-(-)-isoproterenol Homo sapiens 4 cell-based format Scientific Literature 2. ALA3767596 F Agonist activity at rat beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in presence of 40% serum relative to (R)-(-)-isoproterenol Rattus norvegicus 4 cell-based format Scientific Literature 3. ALA3767597 F Agonist activity at rhesus monkey beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay in presence of 40% serum relative to (R)-(-)-isoproterenol Macaca mulatta 4 cell-based format Scientific Literature 4. ALA3767598 A Induction of phospholidosis in human HepG2 cells incubated overnight by LDH assay in presence of fluorescent labeled phospholipid probe NBD-PE Homo sapiens 12 cell-based format Scientific Literature 5. ALA3767599 B Inhibition of human SERT expressed in HEK293 cells preincubated for 30 mins followed by fluorescent substrate addition measured after 30 mins by plate reader analysis Homo sapiens 13 cell-based format Scientific Literature 6. ALA3767766 P Distribution coefficient, logD of the compound at pH 7.4 9 small-molecule physicochemical format Scientific Literature 7. ALA3767767 B Inhibition of human Nav1.2 channel expressed in Xenopus oocytes by two-intracellular microelectrode voltage clamp method Homo sapiens 12 cell-based format Scientific Literature 8. ALA3767768 B Displacement of [3H]-diltiazem from human Cav1.2 channel Homo sapiens 13 single protein format Scientific Literature 9. ALA3767769 B Binding affinity to human ERG channel Homo sapiens 13 single protein format Scientific Literature 10. ALA3767773 B Displacement of [125]I-cyanopindolol from human recombinant beta2 adrenergic receptor after 1 hr by scintillation counting method Homo sapiens 13 single protein format Scientific Literature 11. ALA3767774 B Displacement of [125]I-cyanopindolol from recombinant human beta1 adrenergic receptor after 1 hr by scintillation counting method Homo sapiens 13 single protein format Scientific Literature 12. ALA3768477 F Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay relative to (R)-(-)-isoproterenol Homo sapiens 13 cell-based format Scientific Literature 13. ALA3768478 F Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay Homo sapiens 13 cell-based format Scientific Literature 14. ALA3768479 A Plasma clearance in rat at 1 mg/kg, iv or 2 mg/kg, po Rattus norvegicus 7 organism-based format Scientific Literature 15. ALA3768480 A Plasma clearance in dog at 0.5 mg/kg, iv or 2 mg/kg, po Canis lupus familiaris 5 organism-based format Scientific Literature 16. ALA3768481 A Stability in human plasma assessed as parent compound remaining at 24 hrs by LC-MS analysis Homo sapiens 6 cell-free format Scientific Literature 17. ALA3768482 A Plasma clearance in rhesus monkey at 0.5 mg/kg, iv or 2 mg/kg, po Macaca mulatta 4 organism-based format Scientific Literature 18. ALA3768483 A Unbound clearance in rat at 1 mg/kg, iv or 2 mg/kg, po Rattus norvegicus 4 organism-based format Scientific Literature 19. ALA3768484 A Unbound clearance in dog at 0.5 mg/kg, iv or 2 mg/kg, po Canis lupus familiaris 4 organism-based format Scientific Literature 20. ALA3768485 A Unbound clearance in rhesus monkey at 0.5 mg/kg, iv or 2 mg/kg, po Macaca mulatta 4 organism-based format Scientific Literature