| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3768411 | A | Plasma concentration in rat at 50 mg/kg after 18 hrs | Rattus norvegicus | 1 | ALA3763044 | organism-based format | Scientific Literature | |
| 2. | ALA3768412 | B | Inhibition of HIV integrase N155H mutant | Human immunodeficiency virus | 1 | ALA3763044 | assay format | Scientific Literature | |
| 3. | ALA3768413 | B | Ratio of EC90 for HIV integrase assessed as accumulation of 2-LTR to IC50 for HIV integrase strand transfer activity | Human immunodeficiency virus | 1 | ALA3763044 | assay format | Scientific Literature | |
| 4. | ALA3768414 | T | Mutagenicity in Salmonella typhimurium by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3763044 | organism-based format | Scientific Literature | |
| 5. | ALA3768415 | B | Ratio of EC50 for HIV integrase assessed as accumulation of 2-LTR to IC50 for HIV integrase strand transfer activity | Human immunodeficiency virus | 1 | ALA3763044 | assay format | Scientific Literature | |
| 6. | ALA3768416 | A | Half life in Sprague-Dawley rat at 5 mg/kg, iv and 50 mg/kg, po by LC/MS/MS analysis | Rattus norvegicus | 1 | ALA3763044 | organism-based format | Scientific Literature | |
| 7. | ALA3768417 | A | Oral bioavailability in Sprague-Dawley rat at 50 mg/kg after 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | ALA3763044 | organism-based format | Scientific Literature | |
| 8. | ALA3768634 | P | Lipophilicity Log P of the compound | 1 | ALA3763044 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA3768635 | A | Plasma protein binding in rat by Rapid Equilibrium Dialysis method | Rattus norvegicus | 1 | ALA3763044 | cell-free format | Scientific Literature | |
| 10. | ALA3768636 | B | Inhibition of HCV reverse transcriptase | Hepatitis C virus | 1 | ALA3763044 | assay format | Scientific Literature | |
| 11. | ALA3768637 | B | Inhibition of HCV RNA polymerase | Hepatitis C virus | 1 | ALA3763044 | assay format | Scientific Literature | |
| 12. | ALA3768638 | A | Cytotoxicity against human MT4 cells | Homo sapiens | 21 | ALA3763044 | cell-based format | Scientific Literature | |
| 13. | ALA3768639 | A | Therapeutic index, ratio of CC50 for human MT4 cells to EC50 for luciferase-bearing envelope-defective HIV-1 NL4-3 pseudotype virus infected in human MT4 cells co-infected with HIV1 HXBc2 envelope | 1 | ALA3763044 | cell-based format | Scientific Literature | ||
| 14. | ALA3768640 | F | Antiviral activity against luciferase-bearing envelope-defective HIV-1 NL4-3 pseudotype virus infected in human MT4 cells co-infected with HIV1 HXBc2 envelope after 7 days by multi-cycle assay | Human immunodeficiency virus 1 | 1 | ALA3763044 | organism-based format | Scientific Literature | |
| 15. | ALA3768641 | B | Inhibition of HIV integrase strand transfer activity | Human immunodeficiency virus | 14 | ALA3763044 | assay format | Scientific Literature | |
| 16. | ALA3768642 | F | Antiviral activity against luciferase-bearing envelope-defective HIV-1 NL4-3 pseudotype virus infected in human MT4 cells co-infected with HIV1 HXBc2 envelope by single cycle infection assay | Human immunodeficiency virus 1 | 21 | ALA3763044 | organism-based format | Scientific Literature |
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