# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3767659 | B | Inhibition of OSC in human HL60 cells assessed as accumulation of 2,3-oxidosqualene by GC-MS method | Homo sapiens | 14 | ALA3763134 | cell-based format | Scientific Literature | |
2. | ALA3767660 | F | Inhibition of total cholesterol biosynthesis in human HL60 cells assessed as incorporation of 2-13C-acetate by GC-MS analysis | Homo sapiens | 26 | ALA3763134 | cell-based format | Scientific Literature | |
3. | ALA3767662 | A | Cytotoxicity against human HL60 cells after 24 hrs by MTT assay | Homo sapiens | 26 | ALA3763134 | cell-based format | Scientific Literature | |
4. | ALA3767663 | F | Inhibition of ergosterol biosynthesis in Saccharomyces cerevisiae DSM 1333 at 0.2 to 0.5 times MIC after 48 hrs by GC-MS analysis | Saccharomyces cerevisiae | 8 | ALA3763134 | organism-based format | Scientific Literature | |
5. | ALA3767664 | F | Inhibition of ergosterol biosynthesis in Yarrowia lipolytica DSM 1345 at 0.2 to 0.5 times MIC after 48 hrs by GC-MS analysis | Yarrowia lipolytica | 8 | ALA3763134 | organism-based format | Scientific Literature | |
6. | ALA3767665 | F | Inhibition of ergosterol biosynthesis in Candida glabrata DSM 11226 at 0.2 to 0.5 times MIC after 48 hrs by GC-MS analysis | Nakaseomyces glabratus | 8 | ALA3763134 | organism-based format | Scientific Literature | |
7. | ALA3767666 | B | Inhibition of human OSC expressed in recombinant Saccharomyces cerevisiae SMY8 using [14C]-(3S)-2,3-oxidosqualene as substrate | Homo sapiens | 8 | ALA3763134 | assay format | Scientific Literature | |
8. | ALA3768831 | B | Inhibition of Trypanosoma cruzi OSC expressed in recombinant Saccharomyces cerevisiae SMY8 using [14C]-(3S)-2,3-oxidosqualene as substrate | Trypanosoma cruzi | 8 | ALA3763134 | assay format | Scientific Literature | |
9. | ALA3768832 | B | Inhibition of Saccharomyces cerevisiae FL100 wild type OSC using [14C]-(3S)-2,3-oxidosqualene as substrate | Saccharomyces cerevisiae FL100 | 8 | ALA3763134 | assay format | Scientific Literature |