# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3767720 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
2. | ALA3767721 | A | AUC in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
3. | ALA3767722 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
4. | ALA3767723 | A | Volume of distribution at steady state in Sprague-Dawley rat at 5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
5. | ALA3767724 | A | Clearance in Sprague-Dawley rat at 5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
6. | ALA3767725 | A | Terminal eliminational half life in Sprague-Dawley rat at 5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA3763037 | organism-based format | Scientific Literature | |
7. | ALA3767923 | B | Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysis | Homo sapiens | 55 | ALA3763037 | single protein format | Scientific Literature | |
8. | ALA3767926 | B | Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assay | Homo sapiens | 39 | ALA3763037 | cell-based format | Scientific Literature | |
9. | ALA3767927 | F | Potentiation of temozolomide-induced cytotoxicity in human LoVo cells assessed as temozolomide GI50 at 0.4 uM after 5 days by Celltiter-Glo assay | Homo sapiens | 46 | ALA3763037 | cell-based format | Scientific Literature | |
10. | ALA3767929 | F | Cytotoxicity against BRCA2-deficient human Capan1 cells | Homo sapiens | 42 | ALA3763037 | cell-based format | Scientific Literature |