# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3766985 | Binding | Inhibition of mitochondrial sodium/calcium exchanger in human HeLa cells assessed as reduction in decay rate of histamine-induced mitochondrial calcium at 3 uM after 36 to 48 hrs by aequorin staining based bioluminescence assay | Homo sapiens | 4 | ALA3763035 | cell-based format | Scientific Literature | |
2. | ALA3766986 | Binding | Inhibition of mitochondrial sodium/calcium exchanger in human HeLa cells assessed as reduction in clearance of histamine-induced mitochondrial calcium at 3 uM after 36 to 48 hrs by aequorin staining based bioluminescence assay | Homo sapiens | 1 | ALA3763035 | cell-based format | Scientific Literature | |
3. | ALA3767138 | Functional | Neuroprotective activity against veratradine-induced neuronal cell death in bovine chromaffin cells assessed as cell viability at 10 uM after 24 hrs by LDH release assay relative to control | Bos taurus | 11 | ALA3763035 | cell-based format | Scientific Literature | |
4. | ALA3767949 | Functional | Neuroprotective activity against potassium ion-induced cytotoxicity in human SH-SY5Y cells assessed as cell viability at 3 uM pretreated for 24 hrs measured 24 hrs post potassium ion challenge by MTT assay relative to control | Homo sapiens | 12 | ALA3763035 | cell-based format | Scientific Literature | |
5. | ALA3767950 | Functional | Neuroprotective activity against glutamate-induced neuronal cell death in Sprague-Dawley rat brain hippocampal slices assessed as cell viability at 10 uM incubated 4 hrs by MTT assay relative to control | Rattus norvegicus | 12 | ALA3763035 | tissue-based format | Scientific Literature | |
6. | ALA3767951 | Functional | Neuroprotective activity against rotenone/oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 0.3 uM pretreated for 24 hrs measured 24 hrs post rotenone/oligomycin challenge by MTT assay relative to control | Homo sapiens | 12 | ALA3763035 | cell-based format | Scientific Literature |