# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3767626 | B | Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reader method | Homo sapiens | 52 | ALA3763056 | single protein format | Scientific Literature | |
2. | ALA3767627 | B | Uncompetitive Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate at 110 to 990 nM after 60 mins by Lineweaver-Burk plot analysis | Homo sapiens | 2 | ALA3763056 | single protein format | Scientific Literature | |
3. | ALA3767628 | B | Reversible Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate at IC90 after 60 mins | Homo sapiens | 2 | ALA3763056 | single protein format | Scientific Literature | |
4. | ALA3767629 | B | Inhibition of catalase (unknown origin) using hydrogen peroxide as substrate | Homo sapiens | 2 | ALA3763056 | single protein format | Scientific Literature | |
5. | ALA3767630 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | ALA3763056 | single protein format | Scientific Literature | |
6. | ALA3767631 | B | Selectivity ratio of IC50 for catalase (unknown origin) to IC50 for recombinant human IDO1 | Homo sapiens | 2 | ALA3763056 | assay format | Scientific Literature | |
7. | ALA3767632 | U | Selectivity ratio of IC50 for CYP3A4 (unknown origin) to IC50 for recombinant human IDO1 | Homo sapiens | 2 | ALA3763056 | assay format | Scientific Literature | |
8. | ALA3767633 | B | Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning at 100 uM after 24 hrs by microtiter plate reader | Homo sapiens | 2 | ALA3763056 | cell-based format | Scientific Literature | |
9. | ALA3767634 | B | Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning at 400 uM after 24 hrs by microtiter plate reader | Homo sapiens | 2 | ALA3763056 | cell-based format | Scientific Literature | |
10. | ALA3767635 | B | Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning at 400 uM after 24 hrs by microtiter plate reader | Homo sapiens | 2 | ALA3763056 | cell-based format | Scientific Literature | |
11. | ALA3767804 | A | Cytotoxicity against human HeLa cells assessed as cell viability upto 100 uM by sulforhodamine B assay | Homo sapiens | 2 | ALA3763056 | cell-based format | Scientific Literature | |
12. | ALA3767805 | B | Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production at IC50 after 24 hrs by microtiter plate reader in presence of human serum | Homo sapiens | 2 | ALA3763056 | cell-based format | Scientific Literature | |
13. | ALA3767806 | B | Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by Michaelis-Menton plot analysis | Homo sapiens | 2 | ALA3763056 | single protein format | Scientific Literature |