| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3766219 | ADME | Half life in human liver assessed as carboxylesterase 1-mediated prodrug hydrolysis | Homo sapiens | 9 | ALA3763053 | tissue-based format | Scientific Literature | |
| 2. | ALA3766220 | ADME | Half life in human blood assessed as carboxylesterase 2-mediated prodrug hydrolysis | Homo sapiens | 9 | ALA3763053 | single protein format | Scientific Literature | |
| 3. | ALA3766221 | ADME | Cytotoxicity against human HaCaT cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 11 | ALA3763053 | cell-based format | Scientific Literature | |
| 4. | ALA3766222 | Physicochemical | Dissociation constant, pKa of compound at pH 2 to 12 at 1 to 2 mg by potentiometric titration method | 7 | ALA3763053 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA3766223 | Physicochemical | Octanol-water partition coefficient, log P of compound at pH 2 to 12 by pH metric analysis | 7 | ALA3763053 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA3766224 | Physicochemical | Lipophilicity, log D of compound at pH 7.4 | 7 | ALA3763053 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA3766225 | ADME | Prodrug activation in fetal bovine serum containing medium assessed as cysteamine formation after 24 hrs by LC-MS analysis | Bos taurus | 2 | ALA3763053 | assay format | Scientific Literature | |
| 8. | ALA3766228 | ADME | Prodrug activation in human PT37 cells assessed as intracellular cysteamine-CMQT formation at 20 uM incubated for 2 to 24 hrs by HPLC analysis | Homo sapiens | 6 | ALA3763053 | cell-based format | Scientific Literature |
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