# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3772516 | B | Inhibition of human recombinant KLK4 expressed in Escherichia coli using Bachem I-1120 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
2. | ALA3772517 | B | Inhibition of human recombinant KLK2 expressed in Escherichia coli using Bachem I-1295 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
3. | ALA3772518 | B | Inhibition of human recombinant KLK1 expressed in Escherichia coli using Bachem I-1295 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
4. | ALA3772679 | B | Inhibition of human recombinant KLK8 expressed in Escherichia coli using Bachem I-1120 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
5. | ALA3772680 | B | Inhibition of recombinant uPA (unknown origin) using Biophen CS-61(44) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
6. | ALA3772681 | B | Inhibition of recombinant tPA (unknown origin) using Biophen CS-05(88) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
7. | ALA3772682 | B | Inhibition of human plasma thrombin using Biophen CS-21(66) as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | cell-free format | Scientific Literature | |
8. | ALA3772683 | B | Inhibition of human plasma plasmin using Biophen CS-21(66) as substrate | Homo sapiens | 10 | ALA3769401 | cell-free format | Scientific Literature | |
9. | ALA3772684 | B | Inhibition of factor 10a (unknown origin) using Biophen CS-11(32) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
10. | ALA3772685 | B | Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by 5-5'-Dithiobis(2 nitrobenzoic acid)-based assay | Electrophorus electricus | 10 | ALA3769401 | single protein format | Scientific Literature | |
11. | ALA4373201 | B | Inhibition of Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a using Suc-LY-AMC as substrate preincubated for 10 mins followed by substrate addition and measured over 1 hr by fluorescence assay | Escherichia coli | 106 | ALA4371075 | single protein format | Scientific Literature | |
12. | ALA4373202 | B | Inhibition of Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a at 200 uM using Suc-LY-AMC as substrate preincubated for 10 mins followed by substrate addition and measured over 1 hr by fluorescence assay relative to control | Escherichia coli | 106 | ALA4371075 | single protein format | Scientific Literature | |
13. | ALA4373207 | A | Cytotoxicity against human HeLa cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371075 | cell-based format | Scientific Literature | |
14. | ALA4373208 | A | Cytotoxicity against human HepG2 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371075 | cell-based format | Scientific Literature | |
15. | ALA4373209 | A | Cytotoxicity against human A549 cells after 48 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371075 | cell-based format | Scientific Literature | |
16. | ALA4373210 | T | Selectivity index, ratio of EC50 for human A549 cells to IC50 for Escherichia coli C-terminal His6-tagged ClpP expressed Escherichia coli SG1146a | 2 | ALA4371075 | assay format | Scientific Literature | ||
17. | ALA4373211 | A | Inhibition of bovine alpha-chymotrypsin assessed as residual activity at 200 uM relative to control | Bos taurus | 14 | ALA4371075 | single protein format | Scientific Literature |