# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3772809 | B | Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA3772810 | B | Selectivity ratio of IC50 for human acid ceramidase to IC50 for recombinant human NAAA | Homo sapiens | 6 | assay format | Scientific Literature | ||
3. | ALA3772811 | B | Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
4. | ALA3772812 | B | Inhibition of human acid ceramidase by UPLC/MS analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA3772813 | B | Inhibition of human FAAH at 10 uM by fluorescence assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
6. | ALA3772814 | A | Half life in mouse plasma after 2 hrs by LC/MS-MS analysis | Mus musculus | 6 | cell-free format | Scientific Literature | ||
7. | ALA3772815 | A | Half life in mouse liver microsomes preincubated for 15 mins followed by NADPH addition measured after 1 hr by LC/MS-MS analysis | Mus musculus | 6 | tissue-based format | Scientific Literature | ||
8. | ALA3772816 | A | Half life in rat plasma after 2 hrs by LC/MS-MS analysis | Rattus norvegicus | 6 | cell-free format | Scientific Literature | ||
9. | ALA3772817 | A | Half life in rat liver microsomes preincubated for 15 mins followed by NADPH addition measured after 1 hr by LC/MS-MS analysis | Rattus norvegicus | 6 | tissue-based format | Scientific Literature | ||
10. | ALA3772818 | P | Kinetic solubility of the compound in PBS at pH 7.4 after 24 hrs by UPLC/MS analysis | 6 | small-molecule physicochemical format | Scientific Literature |