# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3772819 | B | Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 30 mins by microplate reader analysis | Homo sapiens | 1 | ALA3769304 | cell-based format | Scientific Literature | |
2. | ALA4003206 | B | Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 1 | ALA4002575 | cell-based format | Scientific Literature | |
3. | ALA4003209 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg after 15 to 1440 mins by UPLC/MS analysis | Rattus norvegicus | 1 | ALA4002575 | organism-based format | Scientific Literature | |
4. | ALA4003216 | A | Half life in mouse plasma at 2 uM after 2 hrs by LC/MS-MS method | Mus musculus | 5 | ALA4002575 | cell-free format | Scientific Literature | |
5. | ALA4177796 | B | Inhibition of recombinant human NAAA expressed in HEK293 cells preincubated for 10 mins followed by PAMCA substrate addition after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA4177521 | cell-based format | Scientific Literature | |
6. | ALA4177798 | A | Oral bioavailability in rat at 10 mg/kg | Rattus norvegicus | 1 | ALA4177521 | organism-based format | Scientific Literature | |
7. | ALA4610468 | B | Inhibition of NAAA (unknown origin) | Homo sapiens | 5 | ALA4609990 | single protein format | Scientific Literature | |
8. | ALA4835860 | B | Inhibition of NAAA (unknown origin) | Homo sapiens | 9 | ALA4834430 | single protein format | Scientific Literature |